The crystal structure has revealed several novel features of PLA2 folding and function. It contains 913 protein atoms and one each of Ca2+, phosphate and acetate ions with 142 solvent water molecules. A Ca2+ ion is present in the calcium-binding loop and forms a seven-fold coordination with...
PURPOSE:To prevent the generation of mutual diffusion on the hetero-interface of multilayer structure on which layers are stacked alternately by a method wherein the title crystal structure has a multilayer structure in which GaAs and AlxGa1-xAs (Al composition ratio Xnot equal to 0) layers are...
DNA recombination is a universal biological event responsible both for the generation of genetic diversity and for the maintenance of genome integrity. A four-way DNA junction, also termed Holliday junction, is the key intermediate in nearly all recombin
Here, we report the crystal structure of a silkworm PIWI-clade Argonaute, Siwi, bound to the endogenous piRNA, at 2.4 Å resolution. Siwi adopts a bilobed architecture consisting of N-PAZ and MID-PIWI lobes, in which the 5′ and 3′ ends of the bound piRNA are anchored by the MID-...
The crystallographic and in silico studies reveal that the naphthalimide ring can be utilized to bind different parts of these enzyme homologs, providing a new starting point to design specific inhibitors. Moreover, Q2-induced closure of the substrate binding pocket is the structural basis for its ...
Crystal structure of the human Tip41 orthologue, TIPRL, reveals a novel fold and a binding site for the PP2Ac C-terminus OPEN V Scorsato,T Lima,G Righetto,... 被引量: 0发表: 2016年 Molecular cloning and characterization of a murine hemicholinium-3-sensitive choline transporter. In ...
Divalent and Oxabridged Neonicotinoids Constructed by Dialdehydes and Nitromethylene Analogues of Imidacloprid: Design, Synthesis, Crystal Structure, and I... A series of divalent and oxabridged neonicotinoids were synthesized by reactions of nitromethylene analogues of imidacloprid and dialdehydes, and ...
we determined crystal structures ofTetrahymena thermophilaPah2 (TtPah2) that directly fuses the N-Lip and C-Lip.TtPah2 adopts a two-domain architecture where the N-Lip combines with part of the C-Lip to form an immunoglobulin-like domain and the remaining C-Lip forms a HAD-like catalytic ...
Crystal and molecular structure of di-(p-nitrobenzoato) tetraquocobalt(II) dihydrate. J Struct Chem 22, 898–902 (1981). https://doi.org/10.1007/BF00746602 Download citation Received22 July 1980 Issue DateNovember 1981 DOIhttps://doi.org/10.1007/BF00746602 Keywords Physical Chemistry Inorganic...
Fig. 1. (A) Crystal structure of MT-I. The overall structure of MT-I is shown as a cartoon representation. Tris molecules (yellow) are illustrated by sticks. (B, C) Interaction of Tris molecules in the MT-I structure of both monomers. Polar contacts are depicted with broken lines, and...