Studies with Ssa/Ssb chimeras show that the peptide-binding domain determines the [PSI+] activity (Allen et al., 2005). It is proposed that Ssa stabilizes an unfolded/prion-competent form of Sup35 whereas Ssb either stimulates refolding into nonprion conformation or targets misfolded proteins ...
It is known that an RNA’s structure determines its biological function, yet current RNA structure probing methods only capture partial structure information. The ability to measure intact (i.e., full length) RNA structures will facilitate investigations of the functions and regulation mechanisms of ...
D. HIV-1 cDNA integration: requirement of HMG I(Y) protein for function of preintegration complexes in vitro. Cell 88, 483–492 (1997). CAS PubMed Google Scholar Llano, M. et al. LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins...
In [42] there is a distinction between function as mediating between structure and behaviour and function as purpose. The first determines the “structural behaviours”, i.e. all possible behaviours the model is able to show. The second restricts the possible behaviours to the “expected behaviour...
How is this damage prevented or controlled, and how does it affect the function of mitochondrial complexes? Is the breakdown of ATP synthase dimers also an effect of oxidative damage, and is it a cause of ageing? It will be challenging to find answers to these questions because many of the...
Rolling path determines orientations of the recrystallized grains. The nuclei of recrystallized grains with basal poles distribution along the TD have a clear advantage over the ones along the RD in the RD-rolled and plates and vice-versa. This is the reason for formation of RD (TD)-split ...
What is the structure of DNA that determines the expression of a trait called? In molecular biology, what is the other name that is used to refer to the structure of DNA? How can the structure and function of nucleotides (DNA and RNA) allow the cell to assemble specific proteins with dif...
Structure-function relationships of wheat flavone O-methyltransferase: Homology modeling and site-directed mutagenesis Jian-Min Zhou, Eunjung Lee, Francesca Kanapathy-Sinnaiaha, Younghee Park, Jack A Kornblatt, Yoongho Lim & Ragai K Ibrahim BMC Plant Biology volume 10, Article number: 15...
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Nucleic acid sequence evolution has an important role in the development of DRBP function. Emerging studies of rapidly evolving lncRNAs suggest that RNA binding by proteins that were previously thought of as DNA-specific may be a widespread phenomenon. ...