Studies with Ssa/Ssb chimeras show that the peptide-binding domain determines the [PSI+] activity (Allen et al., 2005). It is proposed that Ssa stabilizes an unfolded/prion-competent form of Sup35 whereas Ssb either stimulates refolding into nonprion conformation or targets misfolded proteins ...
It is known that an RNA’s structure determines its biological function, yet current RNA structure probing methods only capture partial structure information. The ability to measure intact (i.e., full length) RNA structures will facilitate investigations of the functions and regulation mechanisms of ...
生化英文课件-蛋白质的结构和功能 The_Structure_and_Function_of_Protein 热度: GeneralBiology1 BIO112 Chapter5:Thestructureandfunctionofmacromolecules. Objectives: 1)Listthelevelsofbiologicalhierarchyformsubatomicparticlestomacromolecules. 2)Explainhoworganicpolymerscontributetobiologicaldiversity. ...
What is the structure of DNA that determines the expression of a trait called? In molecular biology, what is the other name that is used to refer to the structure of DNA? How can the structure and function of nucleotides (DNA and RNA) allow the cell to assemble specific proteins with dif...
The relationship between structure, function and regulation in complex cellular networks is a still largely open question. Systems biology aims to explain ... Stelling,Jörg,Klamt,... - 《Nature》 被引量: 970发表: 2002年 Apolipoprotein E: structure determines function, from atherosclerosis to Al...
The latter determines the sequence‐dependent physicochemical properties of DNA, for example its stiffness and susceptibility to strand separation. Most importantly DNA chirality enables the formation of supercoiling under torsional stress. We review recent evidence suggesting that DNA supercoiling, ...
The structure of the protein ultimately determines the function of that protein. Proteins designated for structural roles help maintain cell shape. Other proteins are capable of carrying out biochemical reactions such as those enzymes involved in biosynthesis or cellular respiration. Regulatory proteins ...
Describe the structure, function, and properties of enzymes. Discuss the functions that proteins have. What determines protein function? Enzymes are proteins. Define a protein and explain how the tertiary structure of a protein determines the protein's overall shape and function. ...
A structure–activity relationship is a tool that determines the relationship between the molecular structure of the compound and its bioactivity. For such analyses, quantitative structure–activity relationship (QSAR) modeling has been extensively utilized in medical sciences and toxicology (Nongonierma ...
Describe the function of DNA polymerase I in leading strand synthesis in DNA synthesis. Describe the basic process of DNA replication in a cell. Describe the genetic code and how the nucleotide sequence determines the amino acid and the protein sequence. ...