Boutselakis H, Dimitropoulos D, Henrick K, Ionides J, John M, Keller PA, McNeil P, Pineda J, Suarez-Uruena A, The European Bioinformatics Institute macromolecular structure relational database technology, in Les
SeqHound has been developed as an integrated biological sequence, taxonomy, annotation and 3-D structure database system. It provides a high-performance server platform for bioinformatics research in a locally-hosted environment. SeqHound is based on the
Varadi, Met al. AlphaFold Protein Structure Database in 2024: providing structure coverage for over 214 million protein sequences.Nucleic Acids Research(2024). If you use data from AlphaMissense in your work, please cite the following paper: ...
Studies of the human microbiome have revealed that even healthy individuals differ remarkably in the microbes that occupy habitats such as the gut, skin and vagina. Much of this diversity remains unexplained, although diet, environment, host genetics and
BMC bioinformatics. 2007, 8: 167-10.1186/1471-2105-8-167. Article PubMed Central PubMed Google Scholar Flores S, Echols N, Milburn D, Hespenheide B, Keating K, Lu J, Wells S, Yu EZ, Thorpe M, Gerstein M: The database of macromolecular motions: new features added at the decade ...
With the advancement of sequencing technologies and bioinformatics, over than 170 different RNA modifications have been identified. However, only a few of these modifications can lead to base pair changes, which are called RNA editing. RNA editing is a ubiquitous modification in mammalian transcriptomes...
Considering the availability of the AlphaFold2 Structure Database (DB), which was recently released by the DeepMind team22, our focus is on the 5,042 difficult sequences for which the AlphaFold2 DB models have a confidence score of pLDDT < 0.7. In Fig. 4a, we show the histogram ...
An example of a system that uses visualization techniques to help in high-dimensional clustering is OPTICS [2]. The idea of OPTICS (Ordering Points To Identify the Clustering Structure) is to create a 1D ordering of the database representing its density-based clustering structure. Fig. 43.9 ...
Collaboratory for Structural Bioinformatics (RCSB) Protein Data Bank (PDB) RCSB.org research-focused web portal1, 2, 3 provides open access to a rigorously validated, expertly biocurated collection of ∼200,000 experimentally-determined 3D structures of biological macromolecules stored in the PDB ...
Computational Intelligence Methods for Bioinformatics and Biostatistics(CIBB 2018) Sebastian Daberdaku Part of the book series:Lecture Notes in Computer Science((LNBI,volume 11925)) Included in the following conference series: International Meeting on Computational Intelligence Methods for Bioinformatics and...