To elucidate the function of soluble Fc epsilon RII/CD23 (sFc epsilon RII) the recombinant soluble molecule was produced. This recombinant receptor could competitively block the IgE binding of eosinophils, mono
Hammerstrsm, J.: Structure and function of human effusion macrophages from patients with malignant and benign disease 1. Isolation, morphology, proliferation and phagocytosis. Acta path. micro- biol. scand. Sect. C. 88: 191-200, 1980.
Macrophages are large mononuclear phagocytes that represent the major differentiated elements of the mononuclear phagocytic system. They arise from distinct progenitors in the bone marrow, and their immediate precursors, the monocytes, emigrate from the vascular compartment into many tissues and organs ...
1 The structure and function of the different antibody isotypes are described in Table 20-1. The specificity of an antibody is determined by the amino acid sequence of its antigen-binding site. The variability in sequence that accounts for the enormous diversity of the antibody repertoire is ...
a pivotal early stage in the pathogenesis of atherosclerosis [33]. Vimentin is highly expressed in fiber cells of the eye lens and plays a crucial role in maintaining lens integrity and clear vision. Abnormalities in vimentin filament assembly may also affect the function of the lens, an aberrat...
However, still very little is known on the functional organization of sialyltransferases in the Golgi apparatus and how the sialylation machinery is finely regulated to provide thead hocsialome to the cell. This review summarizes current knowledge on sialyltransferases, their structure–function ...
The cells were lysed with 1% Triton X-100, and an aliquot removed for quantitation of radiolabel. The number of U937 cells or monocytes bound per well was calculated from the initial specific activity (cpm/cell). Spontaneous release of chromium from the monocytic cells in control incubations ...
We determined the doses (0.03 - 3 渭M) at which UA and its analogs blocked metabolic stress-induced acceleration of chemotaxis in response to MCP-1 in metabolically primed THP-1 monocytes. Only the UA analogs hederagenin (IC= 0.64 渭M), oleanolic acid (IC= 1.9 渭M), and uvaol (IC= ...
We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media. By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some...
24.5. 715-237 (1007) 0 FEBS 1997 Leukocyte adhesion Structure and function of human leukocyte P,-integrins and their cellular ligands Carl G. GAHMBERG. Martti TOLVANEN and Pekkn KOTOVUORI Department of Bioscicnces. Division of Biochemistry. University of Helsinki. Finland (Received 31 October ...