Structure, Function, and Activity of Small Molecule and Peptide Inhibitors of Protein Arginine Methyltransferase 1Protein arginine N-methyltransferases (PRMT) are a family of S-adenosyl-l-methionine (SAM)-dependent enzymes that transfer methyl-groups to the 蠅-N of arginyl residues in proteins. PR...
Cell Biosci (2021) 11:13 https://doi.org/10.1186/s13578-020-00522-z Cell & Bioscience REVIEW Open Access Structure, kinetic properties and biological function of mechanosensitive Piezo channels Xiang‑Zhi Fang1,2†, Ting Zhou1,2†, Ji‑Qian Xu1,2, Ya‑Xin Wang1,2...
The plasma membrane environment provides a unique milieu for the regulation of MT1-MMP collagenolytic activity2. However, the manner in which bilayers interact with MT1-MMP has not been examined. A recent study found specific interactions of MMP-12 with bicelles and cells11. In order to ...
Melatonin, through its different receptors, has pleiotropic functions in mammalian brain. Melatonin is secreted mainly by the pineal gland and exerts its effects via receptor-mediated and non-receptor-mediated actions. With recent advancement in neuroanatomical mapping, we may now understand better the ...
While the use of the term AEP seems justifiable for its brevity or if the endopeptidase activity should be emphasised, we generally encourage to use the name legumain, which is consistent with its multiple and still growing functions and in accordance with the recommendations of the Nomenclature ...
Cell Biosci (2021) 11:13 https://doi.org/10.1186/s13578-020-00522-z Cell & Bioscience REVIEW Open Access Structure, kinetic properties and biological function of mechanosensitive Piezo channels Xiang‑Zhi Fang1,2†, Ting Zhou1,2†, Ji‑Qian Xu1,2, Ya‑Xin Wang1,2...
Structure activity relationship (SAR) The biological activity of glycine and glycine interacted with ZnO, MgO, and CaO can be connected to the projected ground state energy and chemical reactivity properties. The energy gap computed at B3LYP/6–31G(d, p) can theoretically explain the chemical ...
The overall structure of PRMT1-RGG-AdoMet complex and Atoms involved in QM region.Ruihan, ZhangXin, LiZhongjie, LiangKongkai, ZhuJunyan, LuXiangqian, KongSisheng, OuyangLin, LiYujun George, ZhengCheng, Luo
factors related to many biological processes, such as plant growth and development, primary and secondary metabolic reactions, different physiological activity and responses to environmental stresses. Cis-elements related to drought- inducibility are also present adequate amount in almost all the promoters....
The extracellular matrix (ECM) is a dynamic set of molecules produced by the cellular component of normal and pathological tissues of the embryo and adult.