Structural isomers of thermo-oxidatively stable poly(carborane-siloxane-arylacetylene) (PCSAA), namely, m-PCSAA and p-PCSAA, were synthesized by the reaction of the dimagnesium salts of m-diethynylbenzene or p-diethynylbenzene with 1,7-bis(chlorotetramethyldisiloxyl)-m-carborane. The ...
Figure 1. (a) The two conformation isomers (left: folded isomer; right: extended isomer) observed in GSH. The extended isomer was confirmed to be the most stable by DFT calculations. (b) Left: the optimized molecular structure of a GSH monomer. Right: the formed dimer as estimated from ...
The purchased BPV is a racemate of dextro-(R)- and levo-(S)-bupivacaine. To investigate if BPV binding has racemic specificity, we performedin-silicodocking simulations. The aromatic ring and the piperidine basic nitrogen of these two isomers largely overlap in site BIG. The primary difference...
Write the molecular formula and draw bond line formulas for each: \\ 1.\ CH_3COOCH_2CH_2Cl\\ 2.\ CH_3CCH_2COH\\ 3.\ (CH_3)_3CC(CH_3)_3 Draw the structural formula for 2-octene, which has a double bond between the number 2 and 3 carbons in th...
Structural isomerism of colloidal semiconductor nanocrystals has been largely unexplored. Here, we report one pair of structural isomers identified for colloidal nanocrystals which exhibit thermally-induced reversible transformations behaving like molecu
Write structural formulas for all constitutional isomers of C_6H_12. Write the condensed structural formula and the formula for 3 pentanol. Write the condensed structural formula and the formula of 3-pentanol. Write condensed structural formula, such as CH3CH3, and describe the molecular geometry ...
X-ray single crystal analysis revealed that in the solid state these salalen group 4 metal complexes formed as single isomers with fac–mer geometry and the two chlorine groups are cis-oriented. Introducing the trans-1,2-cyclohexylene bridge and the electron-withdrawing effects of halide ...
Separation of the cis/trans isomers of the allyl substitution product according to Mulzer/Schülzchen is possible with the tert-butyl ester 46 by using preparative HPLC, but this option had to be ruled out in the present case for practical reasons. However, separation of 46 by column ...
The inhibition of the activity of β-secretase (BACE-1) is a potentially important approach for the treatment of Alzheimer disease. To explore the mechanism of inhibition, we describe the use of 46 X-ray crystallographic BACE-1/inhibitor complexes to der
Amphipathic arginine-rich peptide, A2-17, exhibits moderate perturbation of lipid membranes and the highest cell penetration among its structural isomers. We investigated the direct cell-membrane penetration mechanism of the A2-17 peptide while focusing on structural flexibility. We designed conformationally...