A GTP-binding protein required for secretion rapidly associates with secretory vesicles and the plasma membrane in yeast. Cell 53, 753–768 (1988). Article CAS PubMed Google Scholar Walworth, N.C., Goud, B., Kabcenell, A.K. & Novick, P.J. Mutational analysis of SEC4 suggests a ...
MODELS AND STRUCTURAL FEATURES OF PLASMA MEMBRANEdoi:10.13140/RG.2.2.22670.15689Zahir Hussain
The proposal that rapidly elongating plant cells cannot maintain plasma membrane synthesis by means of the normal endomembrane system has been examined in elongating segments of Avena sativa coleoptiles. Segments were sampled and fixed for electron microscopy, before and after elongation on auxin solutions...
Caveolae are 60–100 nm diameter coated plasma membrane domains that invaginate into the cytosol. They are prominent and common features of the plasma membrane in many cells including adipocytes, fibroblast, and muscle cells1. They concentrate specific lipids including cholesterol, sphingolipids, an...
Isolated rat hepatocyte couplets, consisting of two hepatocytes enclosing a canalicular space, have been proposed as a primary secretory unit that may be useful for direct studies of unmodified canalicular bile secretion. The present study examines their structural characteristics and plasma membrane ...
Large areas of an intermediate layer (most probably the peptidoglycan-containing matrix) have been visualized for the first time between the plasma membrane and the outer membrane of the wall. Extensive regions corresponding to the cytoplasmic face of the plasma membrane have also been obtained. ...
The structural basis for the control by CaM of the gating mechanism itself remains ill-defined. CaM features a two-lobe structural architecture with the N-terminal domain (N-lobe) and the C-terminal domain (C-lobe), and each lobe harbors two Ca2+ binding sites (Babu et al., 1988). ...
Cell membranes are fascinating supramolecular aggregates that not only form a barrier between different compartments, or organelles, of cells but also harbor many chemical reactions essential to the existence and functioning of a cell [1]. For example, the plasma membrane serves as a barrier to pr...
SYTOX Green, a DNA-binding dye, becomes fluorescent when bound to nucleic acids and only enters cells with a compromised plasma membrane. As shown in Fig. 6b, SMAP-18 and G2A did not increase the fluorescence intensity at 2 × MIC like the activity of buforin II. In contrast, similar...
and TM8 at the inner lobe of the plasma membrane (Supplementary Fig.4c, d), which was also found in the maps of hEAAT335and GltPh14(6S3Q and 6 × 15, respectively), suggesting that cholesterol may be correlated to the assembly or function of SLC1 transporters and their homologs....