Primarily as a consequence of the fast sequence evolutionary rate of mouse, the pig has remained considerably more similar at the DNA sequence level to humans [16]. However, some immunological features are exceptional in the pig compared to humans and mice. Pigs have an inverted lymph node ...
substrate, RA patients with active disease and healthy controls significantly differed for specific morpho-structural LN features including median LN volume (p<0.05), vascular flow distribution (grade 3 PD score: 34% in RA vs 0% in controls, p<0.01) and prevalence of cortical hyperthrophy (p<...
Primarily as a consequence of the fast sequence evolutionary rate of mouse, the pig has remained considerably more similar at the DNA sequence level to humans [16]. However, some immunological features are exceptional in the pig compared to humans and mice. Pigs have an inverted lymph node ...
The nucleoside diphosphates linked to moiety-X (NUDIX) hydrolases belong to a super family of enzymes conserved throughout all species1,2, originally called MutT family proteins, as MutT was the founding member. The human MutT homolog MTH1, encoded by theNUDT1gene, has antimutagenic properties,...
Mutational patterns identical to those in the primary tumors were found in 11/12 lymph node metastases (92%, including both BRAFT1799A-positive and -negative cases). The high concordance of the BRAF mutational status in structurally distinct areas suggests a rather homogeneous distribution of ...
This is one of the features of ductal cancer development and over-expression of TIMP-1 and its anti-apoptotic effect may be associated with oncogenic cellular transformation. TIMP-1 levels in serum and TIMP-1 expression in cancerous tissues are associated with poor clinical outcomes in many ...
It has been previously described that in order to form distant metastasis immobile tumor cells undergo epithelial to mesenchymal transition (EMT), a process in which non-invasive cells loose their epithelial character and develop mesenchymal features to eventually acquire more invasive potential. It has...
The APC/C E3 ligase subunit ANAPC11 mediates FOXO3 protein degradation to promote cell proliferation and lymph node metastasis in urothelial bladder cancer Dong Yan Qingqing He Jian Huang Cell Death & Disease(2023) Quantitative real-time in-cell imaging reveals heterogeneous clusters of proteins prior...
ZT Shen,TT Nguyen,KA Daniels,... - 《Journal of Immunology》 被引量: 16发表: 2013年 Disparate Epitopes Mediating Protective Heterologous Immunity to Unrelated Viruses Share Peptide-MHC Structural Features Recognized by Cross-Reactive T Cells. Disparate epitopes mediating protective heterologous immunity...
The genusCorynebacteriumbelongs to the bacterial phylumActinobacteria, also known asActinomycetes. This phylum comprisesMycobacterium,NocardiaandRhodococcusgenera, which together form a supra-generic group known by their initials as CMNR [1–3]. These organisms share some common features, such as: ...