Side effects were noted in 8 of the 19 dogs but were considered mild in all cases. Follow-up times ranged from 12 days to 426 days. When used in conjunction with other appropriate therapies, levetiracetam may be an efficacious option for monotherapy in dogs with structural epilepsy. Its ...
m2internal surface, with access to an outside area of 15 m2. The floor covering in the inner part consisted of wood shavings. Toys were given to these dogs every day and they were released to an enclosed playground. In addition, these dogs lived in an environment handled by the same car...
Increased EP2 transduced signalling is implicated in seizures and epilepsy, whereas its decrease is implicated in glaucoma, bone healing and pulmonary fibrosis. Thus, agonists and antagonists are of potential clinical use. However, in contrast to the EP1 modulators, the field of EP2 modulators has ...
Perception and action, whether in health or disease, depends on connections between brain regions. In general, it is assumed that there is a relationship between the strength of a structural connection between two brain areas and the strength of the corresponding functional connection9. However, it...
Zhang, Z. et al. Altered functional-structural coupling of large-scale brain networks in idiopathic generalized epilepsy.Brain J. Neurol.134, 2912–2928 (2011). ArticleGoogle Scholar Zhang, J. et al. Disrupted structural and functional connectivity networks in ischemic stroke patients.Neuroscience364...
Magnetic resonance imaging in animal models of epilepsy-noninvasive detection of structural alterations. Summary: Small animal magnetic resonance imaging (MRI) has opened a window through which brain abnormalities can be observed over time in rodents noninvasi... Grhn O,Pitknen A - 《Epilepsia》 ...
Background Neurofilament light chain (NfL) is a frequently used biomarker in humans for both diagnostic and therapeutic monitoring purposes in various neurologic diseases. Hypothesis/Objectives It was hypothesized that dogs with diagnosed structural epilepsy (SE) would have a significantly hi...
Objective s : To evaluate the diagnostic value of serum NfL concentration in dogs with intracranial diseases. Animals: Study included 37 healthy dogs, 31 dogs with idiopathic epilepsy (IE), 45 dogs with meningoencephalitis of unknown etiology (MUE), 20 dogs with hydrocephalus, and 19...
The most common chronic neurological disorder in people and dogs is epilepsy with an estimated prevalence of 0.4-1% (Cowan, 2002; Sander and Shorvon, 1996) and 0.6-2% respectively (Schwartz-Porsche, 1986; Kearsley-Fleet et al, 2013). A bit more than twenty per cent of human patients with...
Surgical options for treatment of dogs with drug resistant 'primary' epilepsy are currentlv limited. Transection of the corous callosum4 has been described, but is not widelv in use.Marjorie E. MilneGarry AndersonKathleen E. ChowDayle TyrreU...