Stem cells are one of the foundational evolutionary novelties that allowed the independent emergence of multicellularity in the plant and animal lineages. In plants, the homeodomain (HD) transcription factor WUSCHEL (WUS) is essential for the maintenance
respectively (Fig. 3). The interfacial area between domains is 440 Å2. The active site, defined by the catalytic triad, resides in the ND slightly above the membrane surface with an opening for substrates and products that leads into the bulk membrane. The MD consists of eight transmembra...
The meninges surround the brain and spinal cord, affording physical protection while also serving as a niche of neuroimmune activity. Though possessing stromal qualities, its complex cellular and extracellular makeup has yet to be elaborated, and it rema
To construct alpha rarefaction curves (Fig.1) and estimate differences in the alpha diversity (Fig.2), we removed singletons (OTUs with only one sequence) from the dataset since these singletons could be due to sequencing artefacts. Rarefaction curves were constructed for each individual sample s...
Fig. 3. Differences in peptide conformation are mainly restricted to the terminal functional groups of the P9 amino acid. Detailed view of the F-pocket interactions between the C-terminal cysteine 9, serine 9, and alanine 9 of the wild type, C9S, and C9A analogues of the NY-ESO (157-...
100 μl of diluted hTNF was added to each well of a Greiner Bio One plate (Thermo Scientific, no. 50-823-478), and the plate was incubated at room temperature for 1 h. The plate was washed five times with TBS plus 0.05% (v/v) Tween 20 (TBST) in a plate washer and then ...
Our FFN block has a structure simi- lar to ConvNeXt [36] block with a few key differences, see Figure 2c. We use Batch Normalization as opposed to Layer Normalization, as it can be fused with the preceding layer at inference. Also, it does not req...
The morphological variation within this spe- individuals (n = 154 colonies), as well as visual esti- cies is much larger than differences between some mates of the size and number of any associating C. congenerics (e.g. Acropora) and is expected to influ- retrofasciata were recorded. The...
The triangular heme arrangement in cyt.bdMtbwith its coordinating polypeptide framework and the oxygen entry channel of the mycobacterial enzyme are consistent with structures reported previously (Fig.1e–g)13,14. Apart from these structural similarities, we noted several differences between the structur...
(Supplementary Table6) were diluted in 5% milk/0.05% Tween-20/PBS. Secondary antibodies coupled with HRP were purchased from Invitrogen® and were used according to manufacturer information. All western blots were done in triplicate. Uncropped and unprocessed western blot can be found in the...