Biochemical and structural properties of the protein constituent of junctional domains in eye lens fiber plasma membranes - Benedetti, Dunia, et al. - 1989 () Citation Context ...ypeptide of lens fiber membranes (also called MIP or aquaporine) belongs to a superfamily of putative transmembrane ...
Fibrillin 1, a large glycoprotein enriched in force-bearing tissues, is a prominent constituent of the mouse zonule. In humans, mutations in the gene for fibrillin 1 (FBN1) underlie Marfan syndrome (MS), a disorder characterized by lens dislocation and other ocular symptoms.Fibrillin expression ...
It was found in the insoluble fraction of nuclear fiber cells and localized at the interface between adjacent fiber cells, representing about 0.5% of total protein in adult lens. Its gene with an elaborate promoter region to facilitate lens-specific expression is a common constituent of vertebrate...
crystal structure revealed that TM1 is the main constituent of the pore [15] (Fig.1). The structure also showed that the TM2 lines the pore but in a minor extent, whereas TM3 and TM4 face the hydrophobic membrane environment. The TM1 is tilted, which narrow the pore diameter to 14 ...
Fibrillin 1, a large glycoprotein enriched in force-bearing tissues, is a prominent constituent of the mouse zonule. In humans, mutations in the gene for fibrillin 1 (FBN1) underlie Marfan syndrome (MS), a disorder characterized by lens dislocation and other ocular symptoms.METHODS. Fibrillin ...
This polypeptide is cotranslationatly inserted into microsomal membranes (1, 28) and into isolated lens fiber plasma membranes =-=(8)-=-. The most convincing line of evidence that MP26 is a potential candidate for being the constituent of the communicating pathway between fibers is the amino ...
A major structure/function relationship in the eye lens is that between the constituent proteins, the crystallins and the optical property of refractive index. Structural breakdown that leads to cataract has been investigated in a number of studies; the concomitant changes in the optics, namely ...
In this case, the distribution of the ISOFT component (Figure 3a) unveils areas of tissue encapsulated between wide regions mainly occupied by the IHARD constituent—i.e., the mineralized matrix (Figure 3c). This interpretation of the Brillouin data is also confirmed by the trend of the Raman...
The details on the structure of the KBNNO are explained in a later section. The EDX spectrum was measured on fracture surface of the sintered pellet as shown in Figure 2, suggesting the presence of all the constituent chemical elements. The elemental composition determined by EDX analyses is ...
Here, we present an overview of recent work using SR-µCT, on the applications in structural metals. Keywords: computed microtomography; synchrotron radiation; fracture behavior; laminated structural metals 1. Introduction Better understanding of the fracture behavior is required for the high-...