The human brain’s volume is about equal parts gray matter and white matter. Unlike gray matter, which mainly contains densely packed cell bodies of neurons and glia, white matter is almost exclusively made up of bundles of myelinated axons1. The primary purpose of myelin is to considerably ...
with AE-PG, but not alone, induced a significant antidepressant-like effect in the FST with an increase in the dendritic complexity and the number of dendritic spines in the dentate gyrus (DG) of the hippocampus, revealed by the thin and stubby categories of neurons at...
Prominent proteins at both brain and spinal levels included Type II collagen and Type II keratins, representing extracellular matrix (ECM) and cytoskeletal categories, respectively. While the vast majority of total proteins detected was shared between both meningeal locales, more were uniquely detected ...
Funded by: FundRef https://doi.org/10.13039/501100001809, National Natural Science Foundation of China (National Science Foundation of China); Award ID: 21825703 Award ID: 31971152 Award Recipient : Changlin Tian Pan Shi Categories Subject: Correspondence Custom metadata issue-copyright-state...
Colors of bins in a, colors of communities in b, and colors of edge categories in c are independent and not related to each other. Full size image Exemplars of the surrogate data R, G, T, and GT are presented in Fig. 3a. Spatial layout of GT was very similar to that of the ...
These plastic neural events are discussed in terms of major categories of synaptic morphological change — synaptic density, curvature, and perforations, as well as the size of synaptic elements. The potential functional implications of these morphological changes are reviewed, along with considerations ...
that cleaves the amino- or carboxyl-terminal bonds in the polypeptide chain. The peptidase can also be classified by its principal catalytic residues in active sites such as cysteine, serine, threonine, aspartic, glutamic, metallo, and mixed [11,12] though some categories contain families with tw...
Huntington disease, a neurodegenerative disorder characterized by functional deficits and loss of striatal neurons, is linked to an expanded and unstable CAG trinucleotide repeat in the huntingtin gene (HTT). This DNA sequence translates to a polyglutamine repeat in the protein product, leading to ...
RefSeq genes overlapping rare and structural variants in the autistic subjects and inherited CNVs observed in autism cases were potential enrichment of any functional categories extracted from the UCSC (University of California, assigned to genes overlapping these CNVs. Genotypes Santa Cruz) Genome ...
The p values in this study were tested against two categories of null models. The first null model was based on the spin test. We used a “spin”-based method to correct for potential confounding effects of spatial autocorrelation (https://github.com/frantisekvasa/rotate_parcellation)33. The...