Genetic Deletion of the Stromal Cell Marker CD248 (Endosialin) Protects against the Development of Renal Fibrosis[J]. Nephron, 2015, 131(4): 265 ⁃ 277. DOI: 10.1159/000438754.Smith SW, Croft AP, Morris HL, Naylor AJ, Huso DL, Isacke CM, Savage CO, Buckley CD. Genetic deletion ...
Gene expression profiling suggests that at least a proportion of tumor fibroblasts originate from MSCs (Galie et al., 2007). This notion is also supported by the presence of CD45-PDGFRβ + cells in tumors (Fig. 4). Because MSCs have been shown to function as pericytes (Crisan et al., ...
MSCs grown in the microfluidic device showed a higher level of hepatocyte marker gene expression under hepatic induction. Functional analysis of hepatic differentiation demonstrated significantly higher urea production in the microfluidic device after 21聽days of hepatic differentiation. The microfluidic device...
Paracrine action of mesenchymal stem cells revealed by single cell gene profiling in infarcted murine hearts. PLoS ONE. 2015;10(6): e0129164. Article PubMed PubMed Central Google Scholar Fennema EM, Tchang LAH, Yuan H, van Blitterswijk CA, Martin I, Scherberich A, et al. Ectopic bone...
Mol Cell Endocrinol 248, 87–93 (2006). 8. Igarashi, M. et al. Inductive effects of dexamethasone on the gene expression of Cbfa1, Osterix and bone matrix proteins during differentiation of cultured primary rat osteoblasts. J Mol Histol 35, 3–10 (2004). 9. Park, J. B. The effects ...
However, these osteoblast marker genes remained at low expression levels in Dex-induced osteoporotic cells throughout induction (Figure 2c). By contrast, adipocyte marker gene fatty acid-binding protein-4 (aP2) and glucose transporter type 4 (Glut4) were highly upregulated in Dex-induced ...
Gene markers can help us to distinguish these cell subsets. However, a single gene marker may not fully define the biological function of an MSC subsets. Thus, we need to integrate multiple gene markers to distinguish cell subsets with different biological functions among MSCs. Single-cell RNA ...
Paracrine action of mesenchymal stem cells revealed by single cell gene profiling in infarcted murine hearts. PLoS ONE. 2015;10(6): e0129164. Article PubMed PubMed Central Google Scholar Fennema EM, Tchang LAH, Yuan H, van Blitterswijk CA, Martin I, Scherberich A, et al. Ectopic bone...
HIF-1α promotes bone marrow stromal cell migration to the injury site and enhances functional recovery after spinal cord injury in rats... Xiaoguang,Han,Yong,... - 《Journal of Gene Medicine》 被引量: 0发表: 2018年 Transplantation of dermal multipotent cells promotes survival and wound healing...
Differences in cell proliferation, differentiation, and endometrial receptivity-related gene expression were evaluated. Notably, 10% activated PRP significantly promoted MenSCs proliferation and adipogenic/osteogenic differentiation while suppressing apoptosis. Expression of the mesenchymal stem cells (MSCs) ...