来自 Springer 喜欢 0 阅读量: 2 摘要: Meaning mattress or support for parenchymal cells; Is the connective tissue of an organ or a gland. Historically, stroma was recognized as a supportive or scaffolding component. The stroma is... DOI: 10.1007/978-3-642-16483-5_5532 年份: 2011 ...
The initiation and progression of malignant tumors is driven by distinct subsets of tumor-initiating or cancer stem-like cells (CSCs) which develop therapy/apoptosis resistance and self-renewal capacity. In order to be able to eradicate these CSCs with n
Cancer immunosurveillanceCheckpoint inhibitorImmune cell infiltrationPD-1T cell exclusionTumor infiltrating lymphocytesTumor-stroma spheroidClinically apparent tumors have often established an immunosuppressive tumor microenvironment which renders them "cold," meaning that there are low numbers of immune cells ...
In a paper published inNature Cell Biologyin March 2022, researchers from the University of Tsukuba constructed an atlas of more than 100,000 NHCs collected from 27 human samples, encompassing different types of lymphomas such as follicular lymphomas. The research team used single-cell RNA sequencin...
DNA regions have been differentially used to construct phylogeny at different hierarchical levels, meaning that loci that evolve more slowly are used to analyze higher taxonomic levels, while those that evolve more rapidly are used to analyze relationships between closely related species [4,10,21,22...