A stroke occurs when the supply of blood to the brain is interrupted.Credit: mr.suphachai praserdumrongchai / iStock / Getty Images Plus Stroke is a global challenge, affecting more than 13 million people each year.The majority of stroke patients are left with permanent disabilities that underm...
The largest real-world evaluation of stroke AI imaging, involving more than 80,000 patients at 26 sites over a 3-year period, showed Brainomix 360 Stroke was associated with an additional 50% increase in the number of patients receiving mechanical thrombectomy, while also improving the speed of...
Biomarkers of stroke could improve diagnosis and management, but standardization or harmonization of procedures is needed before translation of biomarkers to clinical practice to ensure results are comparable and reliable. Studies of the proteome of the brain, cerebrospinal fluid and brain extracellular flu...
The Brain-Heart Axis Central autonomic network The heart has its own conduction system, known as the intrinsic cardiac nervous system (ICNS). However, at rest and during physical, emotional, and psychological challenge, heart rate and contractility are modified by the central autonomic network (CAN...
In an uninjured brain, MANF protein is expressed mainly in neurons [14, 40] and its expression levels are increased upon acute ischemia [7, 48, 80]. Interestingly, at 24 h after ischemia, MANF protein expression has been reported also in microglia/macrophages of the ischemic region [60, ...
Anti-epileptic drugs for preventing seizures following acute traumatic brain injury. no evidence that treatment with prophylactic anti-epileptics reduces the occurrence of late seizures, or has any effect on death and neurological disability... A Price - 《Cochrane Database Syst Rev》 被引量: 205...
Pathways of Cerebral Collateral Circulation1 Despite Considerable anatomical proof to the contrary, the myth of "end-artery" circulation to the brain has been perpetuated in textbooks for years. This interpretation of Cohnheim's original theory concerning infarction and his concept... Maurice Tatelman...
CRRL269 is a more potent inhibitor of apoptosis in renal cells and induced less decreases in intracellular Ca2concentration in vascular smooth muscle cells. The renal anti-apoptotic effects were at least mediated by cGMP/PKG pathway. Further, CRRL269 inhibited pro-apoptotic genes expression using a...
We also suggest key priorities for the future, including comprehensive prevention strategies that target people at all levels of CVD risk; implementation of an integrated approach to promote healthy behaviours and reduce health disparities; capitalizing on information technology to advance prevention ...
(Methods). Across stroke types, we identified 110 and 16 95% credible set–trait pairs in European and East Asian participants, respectively, each of which having a 95% posterior probability of containing a causal variant, with multiple credible sets identified at 6 (in Europeans) and 1 (in...