Memory loss tied to stress...Looks at evidence reported by Michael J. Meaney and his colleagues which suggests that stress may be linked with subtle memory and attention problems. Possible role of cortisol; Details of the study.Pennisi
France and 5CNRS FRE2401, Molecular Genetics, Neurophysiology and Behavior, Institute of Biology, Paris, France The activation of glucocorticoid receptors (GR) by glucocorticoids increases stress-related memory through the activation of the MAPK signaling pathway and the downstream transcription factor Egr...
Using pharmacological interventions, we found that D1R antagonist disrupted therapeutic effect of TAAR1 partial agonist RO5263397 on stress-related cognitive and social dysfunction. Knockout TAAR1 in D1-type dopamine receptor-expressing neurons reproduced adverse effects of chronic stress, and TAAR1 ...
Table S1. The transcriptome of CD4+ or CD8+ T cells isolated from NT and ES-treated mice, Related to Figures 2A–2D Table S2. PLS-DA of metabolomic profile in the serum of WT and Miga2TKO mice, Related to Figures 4A–4D Table S3. ScRNA-sequencing of the amygdala from WT mice, Rel...
Hence, related damage functions will then have a clearer physical interpretation. In such a way the proposed models will be more predictive. Another important problem in the modeling of soft biological tissues is the determination of the initial reference (zero stress) state. Soft tissues are ...
A Thermodynamic Approach to Nonlocal Plasticity and Related Variational Principles Elastic-plastic rate-independent materials with isotropic hardening/softening of nonlocal nature are considered in the context of small displacements and s... G.,Borino,P.,... - 《Journal of Applied Mechanics》 被引量...
Aging is associated with structural and functional loss, underlying the reduction of several cognitive skills, such as attention [36], which when associated with stress, may exacerbate age-related cognitive and physical impairment [37], especially in the most vulnerable populations. Stress may affect...
Related Works Stress Prediction and Heart Rate Variability Artificial Intelligence Algorithms AI for Stress Prediction Performance Analysis and Discussion Challanges and Future Scope Conclusion Data Availability References Author information Ethics declarations Additional information Rights and permissions About this ...
The memory of stresses experienced by parents can be passed on to descendants as a forecast of the challenges to come. Here, we discovered that the neuronal mitochondrial perturbation-induced systemic mitochondrial unfolded protein response (UPRmt) in Ca
related disorders, such as anxiety disorders and post-traumatic stress disorder (PTSD) is increasingly appreciated.35,36,37Epigenetics can regulate neuronal plasticity and memory consolidation.38,39,40,41Epigenetic regulation plays a mediating role for abnormal stress response systems, monoamine ...