Diarrhea that originates in the small intestine will cause a dog to defecate at their normal frequency or slightly more frequently. Usually, the stool is watery. A dog whose diarrhea is a large intestine issue, such as colitis, will have very frequent but small bowel movements. These dogs ma...
Studies ofcolitisin a non-human primates (cotton-top tamarin) implicate two coexisting factors as necessary for the initiation and progression ofinflammatory bowel disease(ulcerative colitis) in this model: environmental stress and largeintestinal microflora.156,157,207,208Colitis does not exist in cott...
Inhibition of NF-κB prior to and during inflammation in intact dogs also reversed the suppression of contractility. Transcription factor NF-κB is activated in colonic circular muscle cells by inflammation and oxidative stress. This activation of NF-κB mediates the suppression of cell contractility....
Cecostomy tube lavage for treatment of fulminant clostridium difficile colitis in a recent transplanted patient Fulminant Clostridium Difficile Colitis (FCDC) is a highly lethal disease with mortality rates ranging between 12% 80%. In patients status-post allograft s... Stephanie M Pannell,Marcus J...
Psychosocial stress is a critical inducing factor of inflammatory bowel diseases (IBD), while autophagy is a novel central issue of IBD development. The present study investigated the potential role of autophagy in stress-related IBD in patients and anim
Photodynamic therapy (PDT) is an emerging modality for the treatment of solid tumors. Sinoporphyrin sodium (DVDMS) is a new photosensitizer with good therapeutic killing effects on cancer cells. Recent findings have shown that microRNAs play important roles in many biological processes. However, the ...
In this review the importance of vitagenes in the cellular stress response and the potential use of dietary antioxidants in the prevention and treatment of neurodegenerative disorders is discussed.This is a preview of subscription content, log in via an institution to check access. ...
and modifies intestinal microbiota. Through these various effects at the level of the GI tract, stress is involved in the pathophysiology of irritable bowel syndrome (IBS), a functional digestive disorder, as well as inflammatory bowel disease (IBD), Crohn’s disease, and ulcerative colitis. Targe...
R H Grace, A E Gent, and M D Hellier, Comparative trial of sodium cromoglycate enemas with prednisolone enemas in the treatment of ulcerative colitis, Gut, 1987, 28, 88-92. Scheppach et al., Effect of Butyrate Enemas on the Colonic Mucosa in Distal Ulcerative Colitis, Gastroenterology ...
Persistent and selective effects of inflammation on smooth muscle cell contractility in rat colitis Intestinal inflammation affects smooth muscle contractility contributing to altered motility, but changes to the individual smooth muscle cells are not wel... RW Wells,MG Blennerhassett - 《Pflügers Archiv...