Inflammatory bowel diseases (IBD) are chronic disorders of the intestinal mucosa. As their etiology and pathogenesis are unknown, the influence of psychological strain in IBD remains hypothetical. In this paper a psychoimmunological model of the pathogenesis is presented. Stress in IBD is defined as...
M. (2011). Is metabolic stress a common denominator in inflammatory bowel disease? Inflamm. Bowel Dis. 17 , 2008–2018. 10.1002/ibd.21556 [ Cross Ref ]Schoultz I, Soderholm JD and McKay DM: Is metabolic stress a common denominator in inflammatory bowel disease? Inflamm Bowel Dis ...
Furthermore, single nucleotide polymorphisms in the XBP1 gene are associated with human inflammatory bowel disease. Thus, several lines of crosstalk exist between UPR mediators and inflammatory responses in different organisms, tissues, and diseases. ER stress in liver disease Hepatocytes perform a ...
Psychosocial stress is a critical inducing factor of inflammatory bowel diseases (IBD), while autophagy is a novel central issue of IBD development. The present study investigated the potential role of autophagy in stress-related IBD in patients and anim
Corticosteroidsin measured doses are used to treat many illnesses that are characterized by inflammation or an overactive immune system, such asasthmaandinflammatory bowel disease. For the same reason, they are used to help reduce the chances that our body will immunologically reject a transplanted ...
Cryan JF, O’Mahony SM (2011) The microbiome–gut–brain axis: from bowel to behavior. Neurogastroenterol Motil 23(3):187–192 CASPubMedGoogle Scholar Damman CJ et al (2012) The microbiome and inflammatory bowel disease: is there a therapeutic role for fecal microbiota transplantation? Am J...
GADD34 growth arrest and DNA damage-inducible 34 HCV hepatitis C virus HFD high fat diet HO-1 heme oxygenase 1 HSV herpes simplex virus IBD inflammatory bowel disease IEC intestinal epithelial cells IP3R inositol triphosphate receptor IRE1α inositol-requiring protein-1 JNK Jun-N-terminal kinase...
Stress and anxiety are also known to be a trigger for long-term conditions affecting the digestive system, IBS is often caused by stress, and flare ups of inflammatory bowel disease, like Crohn’s or Colitis, can betriggered by stress. ...
Evaluation of AGR2 and AGR3 as candidate genes for inflammatory bowel disease. Genes. Immun. 7, 11–18 (2006). CAS PubMed Google Scholar Aden, K. et al. ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS–STING. J. Exp. Med. 215, 2868–2886 (2018)...
Epidemiological analysis suggests that stress is associated with the development and progression of chronic inflammatory diseases, such as multiple sclerosis, rheumatoid arthritis, and inflammatory bowel disease (Bisgaard et al., 2022, Herrmann et al., 2000). Psychological stress leads to increased ...