RESULTS. 1,839 culture positive GAS infections and 803 culture positive GAS pharyngitis were identified. 210,104 throat streptococcal antigen tests were positive in the study period. Significant shifts occurred in GAS culture and rapid antigen test positivity during the study period with a decline in...
as well as their observed interaction in the discovery analysis (“FUT2–ABOrisk score”). This was done based on the COPSACseverediscovery cohort by calculating risk estimates between a reference group (homozygous forFUT2 (A)(non-secretor) and forABO (T)(O blood ...
This work was supported by a fund for China Mega—Project for Infecti ous Disease (2011ZX10004—00 1). Correspondence should be addressed to:1) Prof.ZHANG Jian Zho ng,Tel:86—10—58900707,Fax:86-10—58900700, E-mail: zhan鲥ianzhong@icdc.cn; 2) Prof. LUO Feng Ji, Tel: 86—...
Introduction Streptococcus pneumoniae (the pneumococcus) is a Gram-positive bacteria, responsible for acute life-threatening infections including pneumonia, meningitis and sepsis [1], and constitutes the most frequently detected pathogen in cases of community-acquired pneumonia [2]. It is known that ...
However, when oxygen becomes limited, FNR proteins can interact via four N-terminal cysteine residues with [4Fe ˘ 4S] clusters to form homodimers and bind to DNA, leading to transcription activation or repression at specific target promoters [10–12]. FNR-like proteins of Gram-positive ...
The twin supercoiled-domain model proposes that domains of negative and positive Sc are transiently generated behind and ahead of the moving RNA polymerase, respectively [27]. In vitro studies support both this model and a role for TopoI in remov- ing R-loops, which would otherwise interfere ...
All solutions were used according to the manufacturer's instructions (Puregene DNA isolation Kit, Gentra Systems, Minneapolis, MN, USA) for Gram-positive bacteria. PCR assays were performed in a 25 µL reaction mixture containing 0.5 U Taq polymerase (Roche, Mannheim, Germany), 0.5 µM of...