Streptococcus pyogenes (also referred to herein as Strep A or S. pyogenes) is estimated to be the fifth-leading cause of infectious disease deaths globally, behind the human immunodeficiency virus (HIV), Mycobacterium tuberculosis, Plasmodium falciparum, and Streptococcus pneumoniae (although the advent...
Robertson. A mathematical model for the spread of strepotococcus pneumoniae with transmission due to sequence type. Discrete and Continuous Dynamical Systems, pages 553-567, 2011.D. Greenhalgh, K. E. Lamb, and C. Robertson. A mathematical model for the spread of strepotococcus pneumoniae with...
Sip is encoded by a gene in the GBS chromosome; this cell surface protein has been demonstrated as highly conserved; it is present in all GBS serotypes [76,77]. Given this broad distribution, it is unsurprising that Sip has been explored as a candidate for developing a subunit vaccine aga...