In addition, neutrophil-lymphocyte count ratio (NLR) is associated with the related to development of chronic kidney disease (CKD). However, it has not been reported whether development of CKD during long-term
Clinical laboratories play an important role in the diagnosis and monitoring of chronic kidney disease (CKD). Our aim was to evaluate the performance of qualitative and semi-quantitative albumin-to-creatinine ratio (ACR) and protein-to-creatinine ratio (PCR) test strip results as screening tools ...
Conventional disease animal models have limitations on the conformity to the actual clinical situation. Disease-syndrome combination (DS) modeling may provide a more efficient strategy for biomedicine research. Disease model and DS model of renal fibrosis in chronic kidney disease were established by lig...
We also describe how prolonged metabolic stress builds up toxic lipid species in the liver, and how lipotoxicity and metabolic disturbances drive disease progression by promoting a chronic activation of wound healing, leading to fibrosis and HCC. Last, we provide a critical overview of current ...
Autophagy, the intracellular lysosomal degradation process plays a pivotal role in podocyte homeostasis in diabetic kidney disease (DKD). Lysosomal function, autophagic activity, and their actions were investigated in vitro and in vivo. We found that LC3
vesicles derived from fresh ginger could target the colon, promote the repair of damaged mucosa, enhance intestinal repair, and prevent chronic colitis as well as colitis-related cancer [61,192,193]. Extracellular vesicles derived from the Radix et Rhizoma Rhodiolae decoction showed excellent anti-...
OP15 - Do we need a different transfusion strategy in patients with chronic kidney disease undergoing CABG?OP15 - Do we need a different transfusion strategy in patients with chronic kidney disease undergoing CABG?Background and aim: In the present study, we investigated the benefit of ascending...
To prevent the onset of CTLN2, we summarize here the current treatment during NICCD and the adaptation and compensation stage. 2. Citrin metabolism Citrin is an aspartate glutamate carrier (AGC) protein of the mitochondrial inner membrane expressed in the liver, kidney, and heart [21] (Fig. ...
Autophagy, the intracellular lysosomal degradation process plays a pivotal role in podocyte homeostasis in diabetic kidney disease (DKD). Lysosomal function, autophagic activity, and their actions were investigated in vitro and in vivo. We found that LC3
comorbidities continue to interact. Consequently, solely targeting neurodegenerative disease-specific pathologic changes may not be sufficient to achieve the desired outcomes. Halting or reversing the flow of a river would be an effective approach to prevent the boat from moving forwards or even to ...