Several targets and strategies in the development of dengue vaccine have been demonstrated. Currently, Dengvaxia, a live-attenuated chimeric yellow-fever/tetravalent dengue vaccine (CYD-TDV) developed by Sanofi Pasteur, has been licensed and approved for clinical use in some countries. However, this...
After nearly four decades of research, a safe and effective HIV-1 vaccine remains elusive. There are many reasons why the development of a potent and durable HIV-1 vaccine is challenging, including the extraordinary genetic diversity of HIV-1 and its com
There are only four vaccine candidates currently approved for use in humans while many other candidates are at various levels of development. This review seeks to provide updated information on the current nano-technological strategies employed in the development of COVID-19 vaccines....
There has long been interest and demand for the development of a vaccine to prevent infections caused by the Gram-positive organism group A streptococcus. Despite numerous efforts utilizing advanced approaches such as genomics, proteomics and bio-informatics, there is currently no vaccine. Here we re...
The development of immunologic therapies for the treatment of cancer has been limited by many impediments, including means of defining and purifying the ca... Slovin,F Susan - 《Hematology/oncology Clinics of North America》 被引量: 29发表: 2001年 Vaccine therapy of B cell malignancies: differen...
New approaches to HIV vaccine development. potent broadly neutralizing antibodies (bnAbs), in discovery of mechanisms of bnAb induction, and in discovery of atypical mechanisms of CD8T cell killing of HIV-infected cells, have opened new avenues for strategies for HIV vaccine ... BF Haynes - 《...
Several strategies, including the use of adjuvants, development of surface functionalized novel antigen carriers and mucosal immunization for example, have been explored to investigate their role in addressing the limitations associated with the current hepatitis B vaccine. This review focuses on recent ...
The experts also advised WHO on the number of doses of vaccine needed to confer protection, also in different age groups, the co-administration of seasonal and pandemic vaccines, and vaccines for use in pregnant women. Recommendations on the formulation of seasonal influenza vaccines for the south...
Fig. 1: Most advanced SARS-CoV-2 vaccine candidates. The vaccine candidates are grouped according to the platform technology used for their development: mRNA vaccines, replication-defective viral vector vaccines, inactivated pathogen vaccines, protein subunit vaccines, and virus-like vaccines. Manufacture...
Novel Strategies for Immunotherapy in Multiple Myeloma: Previous Experience and Future Directions. Clinical and Developmental Immunology. 2012; 28... Ivetta,Danylesko,Katia,... - 《Clinical & Developmental Immunology》 被引量: 44发表: 2012年 A review of vaccine research and development: The human...