In modulating the actions of cytokines, the strategies used have been broad, including altering affinities of cytokines for their receptors, prolonging cytokine half-lives in vivo and fine-tuning cytokine actions. The field is rapidly expanding, with extensive efforts to create improved therapeutics ...
policymaking and different health issues. In doing so, it aims to identify what has worked for policy actors seeking to advance health in trade-related policy agendas. This aim is important both for policy scholars seeking to understand the mechanisms for change, and for public health advocates w...
molecules. Third, memory T cells persist for very long durations. Some studies have reported that Tcm cells can survive for longer than 10 years. Fourth, memory T cells mediate primary immunosurveillance of peripheral tissues. Tcm cells are present in healthy, noninflamed human skin, lung, colon...
Strategies for Promoting Breastfeeding among Disparate Populations Michal A. Young, MD, FAAP Associate Professor and (I)Chairman, Pediatrics Medical Director, B.L.E.S.S. Howard University College of Medicine Breastfeeding Coordinator, D. C. AAP Disclosure Statement • I ...
In clinical treatment, aspirin (a common NSAID) helps regulate the inflammatory process triggered by Mtb infection by promoting LXA4 production, limiting neutrophil activity, and reducing TNF-α release. This anti-inflammatory effect is important for the treatment of TB meningitis (TBM)[91]. Other...
[243]. In this case, applying the strategy of tumor cell normalization can effectively restore MHC-I expression on tumor cells and thus enhance the efficacy of ICI therapy. For example, epigenetic drugs, HDAC inhibitors, have demonstrated promising results in promoting immune editing of tumor ...
the devastating effects of pulmonary TB, 3D printing technology was employed to create medicinal skin patches. Pharmacokinetic studies in rats revealed the viability of creating 3D-printed medicinal skin patches that may deliver plasma levels for up to 18 days following a single application [248,249...
2018). Electroactive materials that possess electric and electromechanical clues have been proven to be highly relevant in changing cellular behavior and promoting regeneration of a variety of tissues such as bone, cartilage, skin and muscle (Jeon et al. 2020; Liu et al. 2022c) (Table 2). ...
Malignant melanoma is an aggressive form of skin cancer for which there is currently no reliable therapy and is considered one of the leading health issues in the USA. At present, surgery is the most effective and acceptable treatment; however, surgical excision can be impractical in certain circ...
place for NCDs, including the 1) National Strategic Program, with focus on 3 diseases with high mortality rates (cardiovascular disease, cancer, diabetes); 2) Strategic Program for the Prevention and Control of NCDs; 3) Strategy for Promoting Healthy Lifestyles; and 4) Tobacco Control Strategy....