市场关注度提升 TNFR2药物及抑制剂研发机遇和挑战并存 TNFR2又称为CD120b或p75，是肿瘤坏死因子（TNF）受体超家族成员，TNFR2是单程跨膜糖蛋白，由439个氨基酸组成，其能够通过富含细胞半胱氨酸的结构域结合肿瘤坏死因子。TNFR1和TNFR2是TNF的两个受体，与TNFR1不同，TNFR2与跨膜mTNF的亲和力更高，可被mTNF完全...
检测指标:sTNF-R1;sTNFR1;TNF-sR1;TNF-R1;CD120a;p75;肿 瘤坏死因子可溶性受体1;可溶性肿 瘤坏死因子受体1 检测范围:7.8pg/ml~500pg/ml 特异性:系统和其它细胞因子无交叉反应 敏感性:<1pg/ml 产品组成: 组分规格数量 预包被抗人sTNF-RI抗体的96孔板96T1板 ...
肿瘤坏死因子受体(TNFR)蛋白是先天/适应性免疫细胞相互协调的关键,这些蛋白在免疫细胞生命周期中扮演着重要的角色,包括启动、抑制和凋亡等。 2型肿瘤坏死因子受体(TNFR2),又称CD120b或p75,属于TNFR超家族成员,是TNF的受体之一。TNFR2在某些免疫细...
Two different receptors exist for tumor necrosis factor-α (TNF-α), designated as p55 (TNF-RI) and p75 (TNF-RII). Soluble (= s) forms of TNF-Rs are secreted after proteolytic cleavage and block the effects of TNF-α. sTNF-RI, sTNF-RII and the soluble interleukin 2 receptor (sIL-...
本试剂盒所用标准品为重组人sTNF RⅠ,表达从22-211位的氨基酸,分子量为21KDa。检测指标:sTNF-R1;sTNFR1;TNF-sR1;TNF-R1;CD120a;p75;肿瘤坏死因子可溶性受体1;可溶性肿瘤坏死因子受体1检测范围:7.8pg/ml～500pg/ml特异性:系统和其它细胞因子无交叉反应敏感性:<1pg/ml 组分 规格 数量 预包被抗人sTNF-RI...
检测指标:sTNF-R1;sTNFR1;TNF-sR1;TNF-R1;CD120a;p75;肿 瘤坏死因子可溶性受体1;可溶性肿 瘤坏死因子受体1 检测范围:7.8pg/ml~500pg/ml 特异性:系统和其它细胞因子无交叉反应 敏感性:<1pg/ml 产品组成: 组分规格数量 预包被抗人sTNF-RI抗体的96孔板96T1板 ...
别名:TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b 曾用名:TNFR2 全称:tumor necrosis factor receptor superfamily, member 1B TNFRSF1B 分子靶点综述 肿瘤坏死因子受体II (TNF RII)也称为肿瘤坏死因子受体超家族成员1B (TNFRSF1B)。该蛋白与TNF RI形成异源复合物,介导两种具有E3泛素连接酶活性的抗...
CD120b antigen; CD120b; Etanercept; p75 TNF receptor; p75TBPII; p75TNFR; soluble TNFR1B variant 1; TNF RII; TNFBRp80 TNF-alpha receptor; TNF-R2; TNFR2TNFR1B; TNF-R75; TNFR80; TNFRII; TNF-RII; TNF-R-II; TNFR-II; TNFRSF1B; tumor necrosis factor beta receptor; tumor necrosis ...
CD120b; TNFRSF1B; CD120b; CD120b antigen; Etanercept; p75 TNF receptor; p75TBPII; p75TNFR; soluble TNFR1B variant 1; TNFBRp80 TNF-alpha receptor; TNF-R2; TNFR2TNFR1B; TNF-R75; TNFR80; TNF-RII; TNF-R-II; TNFR-II; tumor necrosis factor beta receptor; tumor necrosis factor bindi...
CD120b; TNFRSF1B; CD120b; CD120b antigen; Etanercept; p75 TNF receptor; p75TBPII; p75TNFR; soluble TNFR1B variant 1; TNFBRp80 TNF-alpha receptor; TNF-R2; TNFR2TNFR1B; TNF-R75; TNFR80; TNF-RII; TNF-R-II; TNFR-II; tumor necrosis factor beta receptor; tumor necrosis factor bindi...