胞浆磷蛋白1(STMN1)重组蛋白About the MARKER (complimentary) Effective Size Range:10kDa to 70kDa. Protein bands:10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and 70kDa. Double intensity bands:The 26kDa, 18kDa, 10kDa bands are at double intensity to make location and size approximati...
STMN1Background. Stathmin 1 (STMN1), a marker for immature neurons and tumors, controls microtubule dynamics by destabilizing tubulin. It plays an essential role in cancer progression and indicates poor prognosis in several cancers. This potential protein has not been clarified in clinical patients...
The protein has a calculated MW of 18.1 kDa. The protein migrates as 18 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE). 内毒素(Endotoxin) Less than 1.0 EU per μg by the LAL method. ...
目前最为常用的重组蛋白表达质粒载体融合了复制子(Replicon)、启动子(promoter)、筛选标签(selection marker)、多克隆位点(MCS)和融合蛋白移除策略(fusion tag removal strategy),如图1所示: 胞浆磷蛋白1(STMN1)重组蛋白问题3:成功表达一个重组蛋白,需要的策略组合: 重组蛋白的表达往往不像理论那样一帆风顺,在实际的...
Stathmin in pancreatic neuroendocrine neoplasms: a marker of proliferation and PI3K signaling Serum depletion decreased Ki67 expression (p<0.01) as well as Ser38 phosphorylation (p<0.05) in BON cells. STMN1 knockdown (siRNA) decreased ... S Schimmack,A Taylor,B Lawrence,... - 《Tumour Biology...
These observations suggest that STMN1 might be a drug sensitivity marker not only for taxane agents, but also for several conventional anti-cancer drugs. The association of high STMN1 expression with poor prognosis was observed in patients treated with S-1, but not in patients who received 5-...
FOXM1 that is upregulated in NPC has been identified as potential therapeutic and prognostic marker of NPC [39, 40], which participates in the malignant progress of NPC, including cell cycle progression, proliferation, migration, invasion, apoptosis, angiogenesis, stemness, glycolysis, metastasis, ...
Stathmin1 (STMN1) is a candidate oncoprotein and prognosis marker in several kinds of cancers. This study was aimed to analyze its expression and biologica... K Wei,JHM Tong,AWH Chan,... - 《Plos One》 被引量: 133发表: 2012年
miR-221 inhibition reversed TGF??1 induced EMT by sharply increasing the expression of the epithelial marker E-cadherin and decreasing the expression of the mesenchymal markers vimentin, Fibroactin and N-cadherin. Furthermore, miR-221 expression is positively correlated with malignant potential of ...
Taken together, our results proved that miR-770 could suppress the doxorubicin-resistance and metastasis of TNBC cells, which broaden our insights into the underlying mechanisms in chemo-resistance and metastasis, and provided a new prognostic marker for TNBC cells. 展开 ...