Severe rash, including the Stevens-Johnson syndrome (SJS), is the major toxicity of nevirapine and is described in the package labeling with a prominent, boxed warning. Though physicians treating large populations of patients with HIV are well aware of this complication, only one other report of...
SCARs 主要包括以下 3 种类型:Stevens-Johnson 综合征(Stevens-Johnson syndrome,SJS)/ 中毒性表皮坏死松解症(toxic epidermal necrolysis,TEN)、伴嗜酸粒细胞增多和系统症状的药物反应(drug rash with eosinophilia and systemic symptoms,DRESS)、急性...
Rash in the Severely Ill Patient Stevens-Johnson Syndrome SJS is often a drug reaction, although infections and malignancies have been implicated. Previously, SJS was thought to be linked with EM, but it has recently been reclassified on the spectrum with TEN.2 These patients have diffusely dis...
Typical prodromal symptoms of Stevens-Johnson syndrome are as follows: Cough productive of a thick, purulent sputum Headache Malaise Arthralgia Patients may complain of a burning rash that begins symmetrically on the face and the upper part of the torso. The cutaneous lesions are characterized...
Stevens-Johnson Syndrome Diagnosis To figure out whether you have Stevens-Johnson syndrome, your health care provider will start by asking questions about your medical history, including any medications you've recently started or stopped taking. They'll also take a look at your rash. You may need...
Stevens-Johnson syndrome (SJS) is a rare skin reaction often caused by new medications. Learn the causes, symptoms, what SJS looks like, and treatments.
See also “Overview of blistering skin diseases” and “Rash.” Staphylococcal scalded skin syndrome (SSSS) Mucous membranes are typically not involved in SSSS. SSSS is also much more commonly seen in a younger age group (especially infants). Skin biopsy can be used to confirm the diagnosis....
除上述SJS病例外,Volpe等人还曾报道过一名类风湿关节炎的患者在接受HCQ治疗后躯干及四肢出现了弥漫分布的剥脱性红斑,被诊断为伴有嗜酸性粒细胞增多和全身症状综合症的药疹(drug rash with eosinophilia and systemic symptoms syndrome,DRESS)。在另一项研究中,同样一名类风湿关节炎患者服用HCQ后,出现了SJS的皮肤症状,...
Stevens-Johnson syndrome induced by teriprizumabAuthor information + History + 摘要 1例56岁男性淋巴瘤患者接受特瑞普利单抗(240-mg静脉滴注、1次/3周)联合利妥昔单抗、吉西他滨和奥沙利铂抗肿瘤治疗。首次接受特瑞普利单抗治疗后第5 天,患者全身出现皮疹,躯干和四肢出现大面积红斑,伴瘙痒和疼痛,全身>30%...
诊断:Stevens-Johnson综合征(Stevens-Johnson syndrome,SJS),中毒性表皮坏死松解症评分(SCORTEN)1分;低蛋白血症;肝恶性肿瘤。 治疗:停用多纳非尼,给予静脉滴注甲泼尼龙80 mg/d和白蛋白20 g/d,辅以护胃、补钾、补钙、漱口、局部外用口腔溃疡糊等治疗,病情逐步好转;第8天甲泼尼龙减至60 mg/d,皮疹进一步好转,口腔...