Rituximab is a chimeric mouse/human anti-CD20 antibody licensed for the treatment of low-grade non-Hodgkin’s lymphoma and has recently also been shown to have a role in the treatment of diffuse large B-cell lymphoma. We report a case of Stevens–Johnson syndrome after treatment with rituximab...
Stevens-Johnson Syndrome (SJS) is a severe mucocutaneous drug reaction characterized by epithelial detachment, painful erosions and ulcers on any mucosal body surface, and systemic symptoms. Patients with HIV are susceptible to many complications, including drug reactions. Patients with HIV with SJS ...
Stevens-Johnson综合征(SJS)/中毒性表皮坏死松解症(TEN)是一种严重的皮肤-黏膜反应,绝大多数由药物不良反应引起。该病以水疱及泛发性表皮松解为特征,可伴发一系列系统症状,包括多器官功能衰竭综合征等,具有较高的死亡风险1。然而,由于...
Stevens-Johnson Syndrome Treatment You'll be treated for SJS in the hospital by a special team of doctors and nurses. Some people are treated in a burn center or intensive care unit. The first thing doctors will do is to stop themedicationor treat the infection that made you sick. They'...
Stevens-Johnson综合征/中毒性表皮坏死松解症诊疗专家共识[J] . 中华皮肤科杂志, 2021, 54(5) : 376-381. DOI: 10.35541/cjd.20201177. 2. Pisano C, Brown M, Jambusaria A. A comparison of international treatment guidelines for Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis[J]. Int J ...
Stevens-Johnson 综合征造成的角膜病变非常难治,做角膜移植成功率极低。往往术后角膜上皮不愈合,继续溶解穿孔。偶有不溶解的,也会发生排斥反应,重新血管化。即使做人工角膜也很难成功。这类疾病是目前一个国际难题。 但是这个孩子病变非常重,...
医博士编译自:Yu R, Chen S, Pan Y, et al. Combined use of cyclosporine in the treatment of Stevens-Johnson syndrome/toxic epidermal necrolysis. Journal of Dermatological Science. 2022; 49(6):629-636. https://pubmed.ncbi.nlm.nih.gov/35437858/ ...
Stevens-Johnson 综合征(SJS)是一类少见的严重累及皮肤和黏膜的急性水疱性免疫病,发病率为百万分之一到百万分之七。主要临床表现除了发热、出疹等前驱症状,还有严重的皮肤黏膜症状。 SJS一般为单个患者患病,很少出现爆发的情况。很多专家认为,SJS是一类谱系疾病。SJS...
Stevens-Johnson综合征(Stevens-Johnson syndrome, SJS)/中毒性表皮坏死松解症(toxic epidermal necrolysis, TEN)是严重的药物诱发性皮肤黏膜反应,除支持治疗以外,尚无成熟的药物治疗方法。体外和临床前数据显示,SJS/TEN的角质形成细胞和免疫细胞中,Janus激酶(Janus kinase, JAK)/信号转导及转录激活蛋白(signal transducer...
Stevens-Johnson syndrome (SJS) is a rare skin reaction often caused by new medications. Learn the causes, symptoms, what SJS looks like, and treatments.