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Copyright©1999–2003byMarkBrandt,Ph.D.1SteroidhormonebiosynthesisTheadultadrenalcortexproducesthreeclassesofsteroidhormones:gluco-corticoids,mineralocorti..
Human pregnancy is associated with profound changes in the mother's steroid hormone milieu because of steroids produced by the corpus luteum of pregnancy and by the fetoplacental unit. The precise roles of these hormones in the maintenance of pregnancy, in fetal development, and in parturition have...
On the role of steroid sulfates in hormone biosynthesis The conversion of steroid sulfates to active steroid hormones has been studied. This conversion is limited in the adrenal by the low concentration of steroid sulfatase (SS) present. In contrast, free 5-ene-3尾-hydroxy-steroids are effect....
Our findings indicate that an EDS metabolomic profile is characterized by endogenous and dietary metabolites within the steroid hormone biosynthesis pathway, with some pathways that differ by sex. Our findings identify potential pathways to target for addressing ...
1B). Omics analyses indicated that, other than immunosuppression, impaired steroid hormone biosynthesis, and elevated inflammation, excessive proteasome activity was the most prominent signature in the acute phase of disease among patients with mortality. Based on these data, we developed a new ...
Steroid hormone biosynthesis Author links open overlay panelRalph I DorfmanShow more Add to Mendeley Share Cite https://doi.org/10.1016/0010-406X(62)90013-0Get rights and contentAccess through your organization Check access to the full text by signing in through your organization. Access through...
Moreover, culturing the cells on this ECM enhanced the expression of the 30 kDa steroid acute regulatory protein which plays a key role in steroid hormone biosynthesis. Laminin, but not fibronectin, was able to replace the ECM in ... D Aharoni,I Meiri,R Atzmon,... - 《Cur Biol》 被引...
biosynthesis. Thistransfer of cholesterol is complex but one protein has been shown to be essential for this to occur.Steroidogenic acute regulatory protein, termed StAR protein, is a rapidly turned-over protein in most steroid-producing cells. When the cell is stimulated by a trophic hormone, ...