Abstract #129 Adrenal Insufficiency in a Pregnant Woman with Polyglandular Autoimmune Syndrome Type 2 and Steroid Insensitivitydoi:10.1016/S1530-891X(20)47032-6Neha GulatiAlyson MyersEndocrine Practice
We report a case of M.brisbanense infection in a young man with asthma, recurrent lung infections and secondary adrenal insufficiency induced by inhalation steroids and itraconazole use. The mycobacterial infection was successfully treated with a long‐term multidrug regimen.Rosa Gynthersen...
Here, we have described a primary adrenal insufficiency syndrome and steroid-resistant nephrotic syndrome caused by loss-... R Prasad,I Hadjidemetriou,A Maharaj,... - 《Journal of Clinical Investigation》 被引量: 15发表: 2017年 Cyclosporine in the treatment of steroid-dependent and steroid-...
Glucocorticoids (GCs) are frequently used to treat glomerular diseases but are associated with multiple adverse effects including hypothalamic-pituitary-adrenal axis inhibition that can lead to adrenal insufficiency (AI) on withdrawal. There is no agreed GC tapering strategy to minimise this risk. Method...
Gender-dependent lacrimal protein secretion. Invest Ophthalmol Vzs Sci Suppl. 1986; 27: 25. Google Scholar Ducommun P, Ducommun S, Baquiche M. Comparaison entre l’action du 17-ethyl-19-nor-testosterone et du propionate de testosterone chez le rat adulte et immature. Acta Endocrin. 1959; ...
Additionally, these anxiolytic effects of exogenous neurosteroids are seen in rodents that have been devoid of peripheral neurosteroid secretion, an effect associated with dose-dependent increases in brain levels of neurosteroids (Bitran et al., 1993). Cumulatively, these studies suggest that treatment ...
Selective inhibitors of the dipeptidyl peptidase 4 (DPP-4) enzyme and glucagon-like peptide-1 have shown effectiveness in the control of hyperglycemia since they promote enhanced release of glucose dependent insulin, inhibiting glucagon secretion and enhancing uptake into peripheral tissues, in addition ...
Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors [published erratum appears in E... The conversion of testosterone into dihydrotestosterone by steroid 5 alpha-reductase is a key reaction in androgen action, and is essential both fo...
20 17,20 Lyase activity also requires the phosphorylation of serine residues on P450c17 by a cAMP-dependent protein kinase21 (Figure 13-5). The availability of electrons determines whether P450c17 performs only 17α-hydroxylation or also performs 17,20 bond scission: increasing the ratio of P450...
the POR*28 allele (Zhanget al., 2015). Effects of different POR variations found in nonclinical populations should also be investigated and recent work has shown that some of these variations in POR could lead to severe changes in activities of enzymes dependent on POR (Udhaneet al., 2017)...