This category of ovarian neoplasms includes all those that contain granulosa cells, theca cells and their luteinized derivatives, Sertoli cells, Leydig cells, and fibroblasts of gonadal stromal origin, singly or in various combinations, and in varying de
progestins, androgens), adrenal cortical hormones (glucocorticoids, mineralocorticoids), vitamin D, and insect hormones (ecdysteroids). As discussed in Sect. 3.1, these agents combine with intracellular receptor proteins, converting them to functional transcription factors, ...
Absence of conversion to other steroids: Pregnenolone administration for 8 weeks to patients with schizophrenia or schizoaffective disorder did not result in downstream elevations of cortisol, testosterone, free testosterone, DHEA, androstenedione, or estradiol (Table 6). As pregnenolone is a potential...
By following the procedure of the direct synthesis method up to compound III, a new composition of matter, compound IV', can be made which is chemically the same as compound IV but which exhibits different properties. This is accomplished by adding t-BuOK, or an equivalent, in THF all at...
In patients with SRNS who have attained full remission on CNI therapy for at least 12 months, we suggest considering conversion to MMF as an alternative immunosuppressive agent rather than continuing CNIs (grade C, weak recommendation). Evidence and rationale ...
At the start of the conversion, the volume of the medium with all additives was 100 mL. Biotransformation was carried out at the same temperature as the cultivation. In some experiments, 0.1 mM menadione was added to the conversion medium as EEA [42,43], in the form of suspension in ...
I, cholesterol (cholest-5-ene-3β-ol); II, cholest-4-en-3-one; III, cholesta-1,4-dien-3-one; IV, 26-hydroxycholest-4-en-3-one; V, 3-oxo-cholest-4-en-26-oic acid; VI, 3-oxo-cholesta-1,4-dien-26-oic acid; VII, 26-hydroxycholesterol (cholest-5-ene-3β,26-diol); VIII...
The treatment of our glutamate-damaged PC12 cells with T significantly Molecules 2016, 21, 992 5 of 15 improves the viability of the cells (Figure 1A), which could be related to aromatase conversion in PC12 cells. Despite the great amount of evidence showing the neuroprotective activity of ...