Steric hindrance appears to be the major cause of such inhibition since addition of hapten alone has little effect on BGG binding. An antigen-antigen interaction between KLH and TNP is also detectable. Immune complex formation, steric effects, and antigen-antigen interactions potentially have ...
A major challenge to the successful maturation of the germline forms of VRC01 antibodies toward their broadly neutralizing forms is the steric hindrance imposed by glycan molecules present on the conserved loop D 276 NLGS. As the present germline-targeting Env-based immunogens are designed to specif...
Steric Hindrance in Substitution Reactions on Arsenic Acid by Pentaam(m)ine Complexes of Co~(III) and Cr~(III)reaction mechanismskineticsarsenatesacid catalysisThe kinetics of the substitution reaction of water by H_2AsO_4~- in [M(N)_5(H_2O)]~(3+) (M = Co~(III), Cr~(III)) ...
The kinetics of the substitution reaction of water by H2AsO4– in [M(N)5(H2O)]3+ (M = CoIII, CrIII) complexes have been studied at 25 °C for a series of (N)5 groups, from monodentate (NH3)5 and (CH3NH2)5 to macrocyclic 12-methyl-1,4,7,10-tetraazacyclotridecane-12-...