DepartmentMinDepartmentGuan-YoungDepartmentJeongDepartmentDong-PyoDepartmentJohn Wiley & Sons, Ltd.Angewandte Chemie International EditionSharma, S.; Maurya, R. A.; Min, K. I.; et al. Odorless Isocyanide Chemis
Touchdown PCR (Step-down PCR) like nested PCR, aims to reduce nonspecific background but by gradually lowering the annealing temperature as PCR cycling progresses (Don et al., 1991). The annealing temperature during the initial cycles is usually a few degrees (3–5 °C) above the Tm of th...
The burst thus became less pronounced at substrate concentrations down to 50 µM at 25 °C (Fig. 2b). This is probably because, at lower concentrations, substrate-induced inactivation is rarer, and any enzyme that is deactivated has more time to recover to the active state before ...
The structure of RL is inherently compatible with long, multi-step processes because, instead of attempting to solve the entire reaction space at once, RL can break down decisions into isolated steps and predict the future effects of those steps. One notable example of the potential of RL is ...
Whether as a chemist, engineer, or biochemist, one may be interested in how fast reactants become products in a reaction. Thisrate of reactionis dependent on therate-determining step, the slowest elementary step in the reaction mechanism. Like a line of cars or bikes traveling down a single...
Or more concisely, the reactivity of the reaction sites is independent of chain length. If the viscosity is significantly large and pm cannot be approximated as less than unity, this assumption breaks down, however, for most commercial applications such a large viscosity is undesired therefore not...
In translation, the mRNA copies some portion of DNA that codes for a protein, while in translation, the rRNA clamps down on the mRNA molecule and moves it along like a factory, while tRNA reads the mRNA code and brings the appropriate amino acids, linking many amino acids together to make...
The structure of RL is inherently compatible with long, multi-step processes because, instead of attempting to solve the entire reaction space at once, RL can break down decisions into isolated steps and predict the future effects of those steps. One notable example of the potential of RL is ...
2 are not reaction sites. While substructures produced by our current model are not indicative of actual chemical reactions, and our model has the tendency to break molecules down further than an expert chemist would, it can still fully reproduce the golden reactants when needed. In summary, ...
Therefore, the methyl group in 1a left in a methanol form, which further suggests that this oxidation reaction should involve a hemiketal intermediate. Moreover, the 1H NMR peaks depicted at the typical aromatic region indicates the obvious down-field shift of 2a compared to 1a, which is ...