The craniofacial skeleton comprising the teeth, gums and tongue is an excellent model of organogenesis. Mesenchymal stem cells (MSCs) present within various zones of the oro-dental tissue exhibit exceptional regeneration potential and contribute to tissue restoration and regeneration following infection/...
Stem cells (SCs) are normal, undifferentiated cells that, if exposed to the proper signal, can multiply, produce, and differentiate into a variety of somatic cells in the laboratory and living organisms. Various SCs inside the body are involved in maturation and repair in adult organisms [1]....
Bone regeneration is a complex biological process that relies on the orchestrated interplay of various cellular and molecular events. Bone tissue engineering is currently the most promising method for treating bone regeneration. However, the immunogenicity, stable and cell quantity of seed cells limited ...
Periodontitis is a set of inflammatory diseases of bacterial origin affecting the tissues of the periodontium and provoking the destruction of the tissues that surround and support the teeth. The aim of this article is to report the results obtained with the implantation of stem cells to regenerat...
Using three-dimensional (3D) porous degradable scaffold complexed with mesenchymal stem cells (MSCs) and growth factor gene to improve bone tissue repair and regeneration has raised much interest. This study mainly evaluated the osteogenesis of alveolar bone defects of animal in the following ...
Don't look forclinical trialsyet, but Moradian-Oldak hopes one day their work will result in a gel-filled mouthguard worn overnight that could strengthenteethand reduce their sensitivity. Safeguarding Gums After a tooth extraction, the gum surrounding the tooth's root can be vulnerable to collap...
The hierarchical model of stem cell genesis is based on the idea that the number of cell divisions between the zygote and fully differentiated epithelial cells is kept close to the minimum, which is log to the base 2 of the total number of cells produced in a human lifetime. The model as...
The utility of DPSC has been explored in odontogenic differentiation for tooth regeneration. Alcohol abuse appears to lead to periodontal disease, tooth decay and mouth sores that are potentially precancerous. Persons who abuse alcohol are at high risk of having seriously deteriorated teeth, gums ...
The elimination of sharp or fractured teeth, restorations and prostheses will prevent trauma to the oral mucosa and thus will reduce risk for oral bleeding and infection. The dentist should consider a dental plan that will restore the occlusal surface to the level that will allow the patient to...
Interestingly, we found that the conditioned media from the LPS-preconditioned PDLSCs induced M1 polarization through the extracellular vesicles (EVs), which are released from cells and have been known to be a critical vehicle for intercellular communication [16,17]. 2. Results 2.1. Characterization...