Consequently, development of novel effective therapeutic strategies for COPD is urgently needed. Stem cells were known to differentiate into a variety of cell types and used to regenerate lung parenchyma and airway structures. Stem cell therapy is a promising therapeutic strategy that has the potential...
2024年8月23日,加州大学圣地亚哥分校孙欣实验室在Cell Stem Cell杂志在线发表了题为“Context-dependent roles of mitochondrial LONP1 in orchestrating the balance between airway progenitor versus progeny cells”的研究论文。该研究揭...
Seeking to address this clinical unmet need, a team of researchers from Tongji University (Shanghai, China) conducted a Phase I clinical trial of P63+ autologous lung progenitor cells for the treatment of COPD. The team set out to investigate the safety and efficacy of the therapy in COPD pa...
2024年8月23日,加州大学圣地亚哥分校孙欣实验室在Cell Stem Cell杂志在线发表了题为“Context-dependent roles of mitochondrial LONP1 in orchestrating the balance between airway progenitor versus progeny cells”的研究论文。该研究揭示了线粒体在呼吸道上皮组织发育、稳态维持以及损伤修复中的功能,并且发现线粒体在...
Administration of mesenchymal stem cells into neonatal oxygen-damaged lungs, which results in COPD-like alveoli dysplasia, has been demonstrated to yield improvements in two recent publications [16, 17]. Based on the above rationale for stem cell-based COPD treatments, we began our exploration into...
2024年8月23日,加州大学圣地亚哥分校孙欣实验室在Cell Stem Cell杂志在线发表了题为“Context-dependent roles of mitochondrial LONP1 in orchestrating the balance between airway progenitor versus progeny cells”的研究论文。该研究揭示了线粒体在呼吸道上皮组织发育、稳态维持以及损伤修复中的功能,并且发现线粒体在...
progenitor cells may be a potent next-generation therapy for COPD.Keywords: COPD, regenerative medicine, cell therapy, stem cell, bone marrow, growth ... N Nagaya - 《International Journal of Copd》 被引量: 13发表: 2008年 COPD For Dummies stem cell therapy and its promise for the futureCom...
multi-omics, decellularized lungs, 3D printing, 3D organoids, machine learning algorithms, and organ-on-a-chip methodologies. Registered clinical trials are growing rapidly for studying the feasibility, safety, and benefits of stem cells and their extracellular vesicles for COVID-19 and other respira...
cells at secreting cytokines therapeutic for COPD such as IL-10 [13,14]. Additionally, use of adipose derived cells has yielded promising clinical results in autoimmune conditions such as multiple sclerosis [4]; and c) Pulmonary stem cells capable of regenerating damaged parenchymal tissue have ...
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