Stem cells are cells that have the ability to self-replicate themselves when they divide. They offer the possibility of a source of replacement cells and tissues to treat diseases including Parkinson's and Alzheimer's, stroke, burns, heart disease, diabetes and arthritis.JESSICA ROSE...
Fig. 1.Generation of hESC lines and iPS cells and road map for their clinical utilization. The hESC lines were derived from human blastocysts. At this stage, the blastocyst is comprised of the trophectoderm and the inner cell mass (ICM). ICM cells were isolated, plated on the MEF feeder...
Stem cells (SCs) have been used therapeutically for decades, yet their applications are limited by factors such as the risk of immune rejection and potential tumorigenicity. Extracellular vesicles (EVs), a key paracrine component of stem cell potency, overcome the drawbacks of stem cell applications...
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Cezar,Mark Thiede,Stephen Strom,Toshio Miki,James Trosko.Use and Application of Stem Cells in Toxicology This article summarizes in part the Stem Cell Symposium presented at the 42nd Annual Meeting of the Society of Toxicology, Salt Lake City, Utah, March 2003.Toxicological Sciences. 2004...
In spite of the initial enthusiasm for their potential therapeutic application, SCs are associated with several burdens that can be observed in clinical practice. Firstly, self-renewal and plasticity are properties which also characterize cancer cells and the hypothesis to lose control on transplanted ...
Not all cancer cells are created equal. There are intrinsic differences among cancer cells from the same patient in terms of their ability to proliferate and form tumours in vivo. A subset of cancer cells have the properties of cancer stem cells, which self-renew to generate additional cancer ...
Stem cells are classified according to their differentiation potential: totipotential stem cell, multipotential stem cells and unipotent stem cell. Totipotential stem cell: It has the differentiation potential to form intact individuals, such as embryonic stem cells (ES cells). ...
Stem cells are defined by two important characteristics: the ability to proliferate by a process of self-renewal and the potential to form at least one specialized cell type. Transient population of pluripotent or multipotent stem cells first appear during the development at the first days post coi...
Endometrial stem/progenitor cells are a type of stem cells with the ability to self-renew and differentiate into multiple cell types. They exist in the end