A., et al. (2016). Bispecific T-cell engager (BiTE) antibody construct Blinatumomab for the treatment of patients with relapsed/refractory non-Hodgkin lymphoma: final results from a Phase I study. J. Clin. Oncol. 34, 1104–
例如,在对患有白血病(leukemia)的患者进行治疗时,表达高水平FOXO1的CAR T细胞表现出更好的疗效。 墨尔本的彼得·麦卡勒姆癌症中心(Peter MacCallum Cancer Centre)的团队也通过研究发现,FOXO1能促进CAR T细胞向干细胞样状态的转变。这不仅增强了细胞的持...
Cardiac Events After Radiation Therapy: Combined Analysis of Prospective Multicenter Trials for Locally Advanced Non-Small-Cell Lung Cancer. Purpose Radiation therapy is a critical component in the care of patients with non-small-cell lung cancer (NSCLC), yet cardiac injury after treatment is a .....
The article reports that a successful stem-cell transplant was performed on a Golden Retriever with T-cell lymphoma, a milestone that has spurred hopes of making the procedure customary in the U.S. The Golden Retriever's spleen was removed, and total body radiation treatment was given to kill...
D. The molecular pathogenesis of primary mediastinal large B-cell lymphoma. Blood 118, 2659–2669 (2011). Article CAS PubMed Google Scholar Dieter, S. M. et al. Distinct types of tumor-initiating cells form human colon cancer tumors and metastases. Cell Stem Cell 9, 357–365 (2011). ...
Sep 18, 2024 - This article defines and reviews the potential of stem cell therapy as a promising treatment option for various medical conditions. It also discusses and defines stem cells and their importance in the field of regenerative medicine.
Regenerative medicine is a new and promising mode of therapy for patients who have limited or no other options for the treatment of their illness. Due to their pleotropic therapeutic potential through the inhibition of inflammation or apoptosis, cell rec
Because haematopoietic stem cells (HSCs) can transform into any type of blood cell, they are currently being used in stem cell treatments for various blood cancers and disorders. This includes leukaemia, lymphoma and myeloma. Available today to treat: Metabolic Disorders: Krabbe Disease Hurler Syndro...
Immunotherapy is a promising new form of cancer treatment, but the supercharged immune cells it employs can become exhausted in the fight. Researchers in Japan have found a way to keep them going for longer, by rejuvenating them with stem cells.
Epicardial transplantation of antioxidant polyurethane scaffold based human amniotic epithelial stem cell patch for myocardial infarction treatment Myocardial infarction is a leading cause of death globally. Stem cell therapy is considered a potential treatment. Here, the authors propose an antioxidant polyur...