Serious ethical concerns have been raised regarding stem cell research. Such concerns for example include and are not limited to issues about disruption of embryos to recover usable stem cell lines. This project reviewed the timeline of development for stem cell research with in depth detail of ...
The protracted timeline of maturation is a major bottleneck in generating adult-like neurons from human pluripotent stem cells. We identify a combination of four chemicals that promotes neuronal maturation by repressing epigenetic factors that inhibit it and stimulating activity-dependent factors that promo...
While the proprietary dilemmas currently faced in stem cell science confound many if not all areas of cutting edge life science, they are especially pronounced in the field of stem cell research. First, the tree-like shape of cellular differentiation makes the field especially prone to IPR holding...
Thanks to advancements in stem cell research, particularly the recognition of the regenerative properties ofMesenchymal Stem Cells (MSCs), stem cell therapy may have therapeutic potential for addressing autoimmune conditions, increasing neurological function, promoting anti-aging benefits, and more. Furtherm...
Recently, a unique cell population located at the bronchioalveolar-duct junctions has been proposed to comprise endogenous stem cells for lung regeneration. However, the role of bronchioalveolar stem cells (BASCs) in vivo remains debated, and the contribution of such cells to lung regeneration is...
In adults, MSCs represent a heterogeneous cell population, which also includes multipotent stem cells capable of differentiation into the cartilage, bone, and fat cells. They are often called adult stem cells, as they possess regenerative abilities and are often part of research in the field of ...
Experimental schema and timeline. Rats were anesthetized and subjected to bilateral renal ischemia–reperfusion (I/R) injury or sham surgery. At 24 h post-surgery, rats were randomized into two groups based on creatinine values such that the vehicle-control and treatment groups had similar levels ...
Some initially infected patients had a history of exposure to the Huanan Seafood Wholesale Wet Market, potentially involving animal contact. The virus is thus thought to have a zoonotic origin, after which human-to-human transmission occurred. Its genetic sequences have shown high similarities to ba...
Development of the induced pluripotent stem cell (iPSC) technology.aA timeline of key breakthroughs related to the iPSC technology.b(Top) Somatic cell nuclear transfer (SCNT) experiments were pioneered by John Gurdon in the African clawed frog. Gurdon demonstrated that somatic cells retained all the...
Progression of mesenchymal stem cell regulation on imbalanced microenvironment after spinal cord injury Yifan Liu Chenxi Zhao Shiqing Feng Stem Cell Research & Therapy(2024) Engineered Tools to Advance Cell Transplantation in the Nervous System Towards a Clinical Reality ...