With the development of induced pluripo-tent stem cell technology, it is now possible to reprogram adult cells to differentiate into multiple cell types, including renal cells.1 Although induced pluripotent stem cells hold great promise for treatment of chronic diseases such as kidney failure in ...
Whentreating chronic kidney failure by using stem cells in Europe, lost function of the kidneys is restored, and immune system of the body is significantly strengthened. Injection of stem cells, on the one hand, restore the vessels of the kidney, and on the other – restore the renal tissue...
2024年4月30日,美国南加州大学凯克医学院博德干细胞研究所李中伟团队在Cell Stem Cell期刊发表了题为:Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and dis...
普遍的观点认为干细胞主要通过旁分泌途径分泌多种细胞因子参与组织修复。来自意大利都灵大学的科研团队在《Kidney》上发表的：Exosomes/microvesicles as a mechanism of cell-to-cell communication（外泌体/微泡作为一种细胞间通讯机制）研究证明，细胞间通讯对于保证组织内不同细胞类型之间的适当协调是必需的。干细胞可以...
The prevalence of kidney diseases is emerging as a public health problem. Stem cells (SCs), currently considered as a promising tool for therapeutic application, have aroused considerable interest and expectations. With self-renewal capabilities and grea
2024年4月30日,美国南加州大学凯克医学院博德干细胞研究所李中伟团队在Cell Stem Cell期刊发表了题为:Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease 的研究论文。
cells (hiPSCs) are stem cells that can differentiate into many different cell types. They hold tremendous potential for studyinggenetic diseases; the drawback has been that differentiation into certain cell types has been problematic. Such is the case with many cell types found in the kidney. ...
With the increasing rate of end-stage renal failure and limited alternatives for its treatment, stem cell (SC) therapy for kidney injury is urgently needed. Choosing the right SC type is the critical step in realizing the potential of this therapeutic approach. Four possible sources of SCs are...
Functional recovery in acute renal failure is well known, and the adult kidney is generally recognized to have the capacity to regenerate and repair. Sever... K Hshkawa - 《Hypertension Research》 被引量: 69发表: 2006年 Stem-cell therapy for renal diseases Significant attention is currently dir...
近日,来自美国华盛顿大学的Benjamin S. Freedman团队在Cell Stem Cell期刊发表题为Genetics of cystogenesis in base-edited human organoids reveal therapeutic strategies for polycystic kidney disease(碱基编辑人类类器官中囊肿生成的遗传学揭示多...