2024年9月30日,武汉大学医学研究院、教育部免疫与代谢前沿科学中心、泰康生命医学中心、武汉大学中南医院张楹团队在Cell Stem Cell杂志上在线发表了题为Epitope prime editing shields hematopoietic cells from CD123 immunotherapy for acute ...
2024年9月30日,武汉大学医学研究院、教育部免疫与代谢前沿科学中心、泰康生命医学中心、武汉大学中南医院张楹团队在Cell Stem Cell杂志上在线发表了题为Epitope prime editing shields hematopoietic cells from CD123 immunotherapy for acute myeloid leukemia的研究论文,介绍了一种基于碱基编辑器和先导编辑器的抗原表位精...
Cancer stem cells in the blood: Possible therapeutic implications[J].Liver transplantation: official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2008,7(7).Perkins JD.Cancer stem cells in the blood:possible therapeutic im-...
[4] Bartucci M, Dattilo R, Martinetti D, Todaro M, Zapparelli G, Di Virgilio A, Biffoni M, De Maria R, Zeuner A. Prevention of chemotherapy-induced anemia and thrombocytopenia by constant administration of stem cell factor. Clin Cancer Res. 2011 Oct 1;17(19):6185-91. doi: 10.1158/...
近日,来自美国希望之城国家医疗中心血液学与造血细胞移植科的Jianhua Yu与Michael A. Caligiuri共同在Cell Stem Cell期刊发表题为Human anti-PSCA CAR macrophages possess potent antitumor activity against pancreatic cancer(人类抗PSCA CAR...
A human lymphoma organoid model for evaluating and targeting the follicular lymphoma tumor immune microenvironment 杂志:Cell Stem Cell 影响因子:23.90 发表时间:2024年2月 作者及单位:美国加利福尼亚大学Lisa E. Wagar;斯坦福大学Ash A. Alizadeh等
Introduction The cancer stem cell model for tumor progression is the first model of its type to suggest that only one subpopulation of cancer cells is capable of proliferating indefinitely. These cells resemble normal stem cells in their capacity for self-renewal and multi-potential differentiation, ...
骨髓增生异常综合征(Myelodysplastic syndromes,MDS)是一组起源于造血干细胞(hematopoietic stem/progenitor cell,HSC)的克隆性疾病,以血细胞病态造血,高风险向急性髓系白血病(Acute myelogenous leukemia, AML)转化为特征。除了异基因造血干细胞移植,迄今尚无精准有效的治愈MDS的方法。阐明MDS干细胞特性得以维持的分子机制仍...
目前研究方向包括血液系统细胞命运转化的调控机制、急性髓系白血病发病机制与靶向等。近三年来已在Cell Stem Cell(2022;2021;2020)、Blood(2021详见BioArt报道:Blood | 张好建团队揭示RNA结合蛋白YBX1在急性髓系白血病中的分子机制)、Cell ...
Bad blood? But what about the rogue red cell that slips through the filter with its cancer genes still intact? Lanza calls these cells “escapees.” “When you’re dealing with such huge numbers of cells,” said Lanza, “there may be a few of these cells that would slip in.” ...