In today's scenario, one of the most widespread uses of stem cells is bone marrow transplantation, and it has revolutionized the treatment of some cancers. Although stem cell therapy is yet to be introduced in many other clinical practices, it is progressively being evaluated as a treatment ...
Stem cell models of organogenesis are a valuable tool for the study of human development, but often lack the context of tissue-tissue interaction. Here they generate human multi-lineage organoids comprising pro-epicardium, septum transversum, and liver bud, which they co-culture with heart organoi...
that is the ability not only to divide themselves rapidly and continuously, but also to create new SCs and progenitors more differentiated than the mother cells. The asymmetric mitosis is the process which permits to obtain two intrinsically different daughter cells. A cell polarizes itself, so th...
explaining why researchers switch from stem cell research to EVs research. Then, we briefly describe the applications of 2D-EVs and the existing clinical studies related to EVs. Next, we introduce the history of 3D cell culture and the existing 3D cell culture...
A. Stem cells in normal and leukemic hemopoiesis (Henry Stratton Lecture, 1982). Blood 62, 1–13 (1983). CAS PubMed Google Scholar Trott, K. R. Tumour stem cells: the biological concept and its application in cancer treatment. Radiother. Oncol. 30, 1–5 (1994). CAS PubMed Google ...
A stem cell is functionally defined by its multipotency and self-renewing capacity.Intestinal stem cells’ progeny undergo lineage differentiation into the limited intestinal epithelial cell types. To achieve this, stem cells must divide to give rise to a daughter stem cell and a committed daughter...
Current state of stem cell research and its application in South Africa. [http://embrybros.wordpress.com/2011/04/06/current-state-of-stem-cell-research-and-its-application-in-south-africa/] South African bone marrow registry annual general meeting. [http://www.sabmr.co.za/agm2008report.pdf...
Stem-cell differentiation is the process by which a more specialised cell is formed from a stem cell, leading to loss of some of the stem cell's developmental potential. Stem-cell differentiation occurs during development of an organism to produce new specialised cells, and also in adults to ...
Mesenchymal stem cells (MSCs) have been extensively investigated for their potential applications in regenerative medicine and cell therapy. For developing effective stem cell therapy, the mass production of consistent quality cells is required. The cell culture medium is the most critical aspect of ...
other hand, ESCs, iPSCs, and adult stem cells have only been used to generate tissues and organs. In recent years, and especially in the last decade, stem cell research has blossomed into an exciting and promising field. Stem cells, especially ESCs and iPSCs have shown great application ...