Hematopoietic Cell Growth FactorsCell AgingCell DivisionThe limited life-span of most blood cells requires continuous production of cells which in adults may exceed 1012 cells/day. This impressive production of cells ( 4.1015 cells over a life time) is achieved by the proliferation and ...
The current supply of red blood cells expressing rare blood groups is not sufficient to cover all the existing transfusion needs for chronically transfused patients, such as sickle cell disease homozygous carriers, because of alloimmunization. In vitro production of cultured red blood cells is slowly...
As a consequence, the current model of blood supply has to be strengthened, and new sources of red blood cells (RBC) are welcome. A cell therapy approach, in which so-called 'cultured RBC' (cRBC) are generated invitro, might be a solution. We report here on the various obstacles that...
They’re the only way to cure sickle cell disease.Stem cellsare cells in your bone marrow that grow into new red or white blood cells and platelets (cells that help formblood clots). Using this treatment is risky and relatively new for treating SCD. It hasn't been compared to the usual...
"This team has made a significant contribution to scientists' quest to produce red blood cells in the lab," said Atala, who is also director of the Wake Forest Institute for Regenerative Medicine. How does the new process work? "We combined different cell-expansion protocols into a 'cocktail...
“Using your own cells to generate blood stem cells could eliminate the need for donor blood transfusions or stem cell transplantation. Unlocking mechanisms used by nature brings us a step closer to achieving this goal,” Prof. Pimanda said....
Blood Transfusion, AutologousErythropoiesisRed cell production in vertebrates is controlled by a glycoprotein hormone known as erythropoietin (Ep), which is ... SE Graber,Sanford B. Krantz - 《Hematology/oncology Clinics of North America》 被引量: 115发表: 1989年 Ex vivo generation of human red ...
Peripheral blood stem cell apheresis in low-weight children: A single centre study Amir Hossein Norooznezhad, ... Ardeshir Ghavamzadeh, in Transfusion and Apheresis Science, 2019 1 Introduction Nowadays, peripheral blood stem cell transplantation (PBSCT) is a curative therapy for hematological diseases...
Clinic and Transfusion Urine drainage Miscellaneous Warming SAHARA 4 SAHARA-III Stem cells Accessories Stripping Laboratory automation Product Search Stem cells Our SAHARA-TSC enables the quick, dry and temperature-controlled thawing of blood stem cell preparations. These can either be actively warmed us...
Platelets, actually blood cell fragments, are formed in bone marrow from giant cells with multilobed nuclei called megakaryocytes. The main function of platelets is to help blood to clot. 血小板,实际上是血细胞碎片,是由骨髓中的多核巨细胞分...