Free Radical Biology & MedicineLiu J, Cao L, Finkel T. (2011) Oxidants, metabolism, and stem cell biology. Free Radic Biol Med 51,2158-2162.Liu J, Cao L, Finkel T. Oxidants, metabolism, and stem cell biology. Free Radic Biol Med. 2011; 12 :2158–2162. doi: 10.1016/j.freerad...
Thus plant stem cells depend on the function of other, neighboring, cells to continue behaving as stem cells, and therefore some sort of signal must be passed between cells to maintain stem cell behavior. In animals, the signaling molecules used within stem cell niches are often the same used...
2022年8月22日,Pura Muñoz-Cánoves课题组在Cell Stem Cell上发表了题为:Mitochondrial dynamics maintain muscle stem cell regenerative competence throughout adult life by regulating metabolism and mitophagy的研究论文,首次呈现了...
Here, we review the similarities and differences in the metabolism of stem cells from several tissues and highlight the mitochondrial metabolic checkpoint in stem cell maintenance and aging. We discuss how diet engages the nutrient sensing metabolic pathways and impacts stem cell maintenance. Finally,...
Lipid metabolism regulates stem cell states and differentiation. Here, the authors demonstrate a requirement in planarians for Apolipoprotein B-mediated neutral lipid transport from intestinal stores to stem cells and their progeny during differentiation and whole-body regeneration. ...
Defective cholesterol metabolism in haematopoietic stem cells promotes monocyte-driven atherosclerosis in rheumatoid arthritis 来自 Semantic Scholar 喜欢 0 阅读量: 47 作者: D Dragana,MJ Kraakman,PR Nagareddy,N Devi,S Waled,HL Kammoun,W Alexandra,LMK Sam,AS Annas,P Gerard 展开 摘要: Background ...
7月12日,最新一期的Cell Stem Cell杂志在线发表了美国洛杉矶加州大学(UCLA)王存玉和俞波教授团队题为PGC-1α Controls Skeletal Stem cell Fate and Bone-Fat Balance in Osteoporosis and Skeletal Aging by Inducing TAZ的论文,首次揭示了PGC-1α在干细胞命运抉择与骨脂平衡的调控中的作用。作者发现,随着年龄增长,...
HSCs rely on glycolysis rather thanoxidative phosphorylation(OXPHOS) for ATP production, and this unique energy metabolism protects HSCs fromoxidative stressbyreactive oxygen species(ROS) [31,32]. To suppressOXPHOS, mitochondrial activities are maintained at low levels in HSCs by fine-tuned quality con...
Stem Cell Metabolism Joshua M. Brickman, Ph.D., University of Copenhagen, Denmark Weiping Han, Ph.D., Singapore Bioimaging Consortium, Singapore Stem Cell Niches Paul S. Frenette, M.D., Albert Einstein College of Medicine Kim B. Jensen, Ph.D., BRIC - Biotech Research & Innovation Centre,...
Cells can modify metabolism using different energy sources to enhance their survival and maintain homeostasis. With regards to the heterogeneity of tumor cells, CSCs show higher metabolic plasticity compared to normal cancer cells [20]. In non-stem, highly proliferative cancer cells, glycolytic ...