In case of neoadjuvant chemotherapy, clinical node positivity or a macrometastasis on pretreatment sentinel node biopsy was an indication for regional RT, regardless of the type and results of postchemotherapy axillary staging. After neoadjuvant chemotherapy, any size of axillary metastasis was an ...
The median mast cell density observed on excisional biopsy of patients with MCPyV negative status is significantly higher than the median observed on excisional biopsy of patients with MCPyV positive status (6.1 vs 2.2; p = 0.048) (Fig. 4). Furthermore, MCPyV status is associated with recur...
Sentinel lymph node (SLN) biopsy significantly improves axillary lymph node (ALN) staging. Simultaneously, using haematoxylin and eosin (H&E) staining and immunohistochemistry (IHC), we further delineated ALNS. According to the size of the tumour lymph node metastases, we divided them into macro...
Second, although three cohorts performed strict inclusion criteria, liver biopsy was performed in only one cohort, and the diagnosis of NAFLD in the other two datasets was conducted in clinical settings. Therefore, the accuracy and the content of NAFLD may be heterogenous among them. In addition,...
(95% CI, 0.81–0.87) in detecting NAFLD, there may have been participants with unidentified NAFLD that could have been detected by ultrasonographic evaluation or liver biopsy. However, FLI is a low-cost and convenient method that only requires a blood test and is commonly performed in routine ...
cancers Review Emerging Lab-on-a-Chip Approaches for Liquid Biopsy in Lung Cancer: Status in CTCs and ctDNA Research and Clinical Validation Ângela Carvalho 1,2,3,* , Gabriela Ferreira 1,2,3, Duarte Seixas 1,2,3,4 , Catarina Guimarães-Teixeira 3,4, Rui Henrique 3,4,5,6 , ...