Status epilepticus is defined as 5 or more minutes of continuous clinical and/or electrographic seizure activity, or recurrent seizure activity without recovering to baseline between seizures. The history and neurological exam are essential to initial detection of SE. Some patients may present with ...
Status epilepticus in adults The definition of status epilepticus as a prolonged seizure or a series of seizures with incomplete return to baseline is under reconsideration in an effort... JP Betjemann,DH Lowenstein - 《Lancet Neurology》 被引量: 104发表: 2015年 Status epilepticus in adults The...
难治性癫痫持续状态(Refractory status epilepticus RSE)是指连续癫痫发作持续30min 或两次或多次发作间歇期意识未完全恢复的状态,给予合适剂量的一种初始苯二氮卓类及一种非苯二氮卓类抗癫痫药物后仍无法终止的持续性惊厥性或非惊厥性癫痫...
Most children with an episode of SE should be admitted for inpatient observation, evaluation, and treatment. Any child with persistent altered mental status (despite cessation of seizure activity) or with prolonged status epilepticus should be admitted to a pediatric critical care unit. Treat patients...
Since the publication of the Italian League Against Epilepsy guidelines for the treatment of status epilepticus in 2006, advances in the field have ushered in improvements in the therapeutic arsenal. The present position paper provides neurologists, epileptologists, neurointensive care specialists, and...
Pediatric convulsive status epilepticus (cSE) is a neurologic emergency with potential for morbidity and mortality. Rapid treatment and escalation of therapies to achieve early seizure control is paramount in preventing complications and providing the best patient outcomes. Although guidelines recommend early...
Engel T, Gomez-Villafuertes R, Tanaka K, Mesuret G, Sanz-Rodriguez A, Garcia-Huerta P, Miras-Portugal MT, Henshall DC, Diaz-Hernandez M (2012b) Seizure suppression and neuroprotection by targeting the puri- nergic P2X7 receptor during status epilepticus in mice. FASEB J 26:1616 - 1628....
Aims Focal nonヽonvulsive status epilepticus (FncSE) is a common emergency condition that may present as the first epileptic manifestation. In recent years, it has become increasingly clear that de novo FncSE should be promptly treated to improve post﹕tatus outcome. Whether seizure activity occur...
Hippocampal transcriptome after status epilepticus in mice rendered seizure damage-tolerant by epileptic preconditioning features suppressed calcium and ne... etal.Hippocampal transcriptome after status epilepticus in mice rendered seizure damage-tolerant by epileptic preconditioning features suppressed calcium and...
Status epilepticus represents a challenging condition in which therapy needs to be balanced between both the risks of over- and undertreatment. While the first may lead to iatrogenic harm [1–3], the latter carries the risk of prolonged seizure activity and thus neuronal damage [4]. Early knowl...