Department of Paediatric Neurology, Bristol Royal Hospital for Children, Upper Maudlin Street, Bristol BS2 8BJ,UKElsevier LtdCurrent PaediatricsBasu H, O'Callaghan F. Status epilepticus: beyond guidelines. Curr Paediatr. 2005;15:324-32.Basu H, O' Callaghan F. Status epilepticus: beyond guidelines...
INTRODUCTION Epilepsy is the most common serious neurological disorder, affecting approximately 1 in 150 people in the UK (Sander 2003), and status epilepticus is sometimes described as the maximal expression of epilepsy, being associated with both short- and long-term significant mortality and morbidi...
The etiologies of SE episodes can be classified as (1) acute symptomatic, (2) chronic-progressive neurologic disorders, and (3) remote symptomatic status epilepticus. Acute symptomatic status epilepticus may be caused by an acute infection, head trauma, hypoxemia, hypoglycemia, or drug withdrawal. ...
Status epilepticus (SE) is a life-threatening neurological disorder. The hippocampus, as an important area of the brain that regulates cognitive function, is usually damaged after SE, and cognitive deficits often result from hippocampal neurons lost after SE. Fyn, a non-receptor Src family of tyr...
reported a mortality of 3% in 91 children admitted with confirmed status epilepticus; all deaths were in children with an acute symptomatic or progressive cause of CSE.15 The overall reduced mortality may be explained by a change in the definition of CSE (1 h duration in the 1970s, in ...
Simplified scheme of biochemical changes in blood serum, western blots, and photomicrographs of hippocampi ofProechimys guyannensisfemale with or without ovariectomy. (a) Biochemical and hormonal changes in serum and protein expression in NOVX and OVX animals with status epilepticus (SE). (b) Co-...
In adults, status epilepticus represents after stroke one of the most frequent neurological emergencies. Depending on the type and duration of seizures, it can induce considerable morbidity and mortality, therefore requiring immediate management. International guidelines recommend a stepwise approach, where ...
Pediatric convulsive status epilepticus (cSE) is a neurologic emergency with potential for morbidity and mortality. Rapid treatment and escalation of therapies to achieve early seizure control is paramount in preventing complications and providing the best patient outcomes. Although guidelines recommend early...
INTRODUCTION Epilepsy is the most common serious neurological disorder, affecting approximately 1 in 150 people in the UK (Sander 2003), and status epilepticus is sometimes described as the maximal expression of epilepsy, being associated with both short- and long-term significant mortality and ...
SE status epilepticus Sub subiculum TLE temporal lobe epilepsy VGLUT1 vesicular glutamate transporter 1 1. Introduction A single episode of sustained status epilepticus (SE) can be the cause for mesial temporal lobe epilepsy (TLE), both in patients and in experimental animals (Lothman and Bertram...