Atorvastatin (Lipitor) Lovastatin (Mevacor) Simvastatin (Zocor) The ones that have little or no effect from grapefruit juice are: Fluvastatin (Lescol) Pitavastatin (Livalo) Pravastatin (Pravachol) Rosuvastatin (Crestor) Get Relief from Statin Side Effects Your doctor may be able to suggest some way...
Statins currently available in the UK are atorvastatin, fluvastatin, pravastatin, rosuvastatin and simvastatin. Like all medications, statins may cause side effects in some people. Most side effects occurring during statin treatment are of mild intensity. The current product information for each statin ...
Of all statins, simvastatin and atorvastatin areresponsible for most reported incidents of liver damage, but this is likely just due to the fact that they are prescribed the most. The Spanish Hepatotoxicity Registry identified 858 cases of drug-induce liver injury. Which statin has the least amoun...
WHAT ARE NAMES OF STATINS? Genericand brand names of statins drugs include: Amlodipine/atorvastatin (Caduet) Atorvastatin (Lipitor) Atorvastatin/ezetimibe (Liptruzet) Fluvastatin (Lescol) (Lescol XL) Lovastatin (Altoprev) (Mevacor) Lovastatin/niacin(Advicor) Pitavastatin (Livalo) (Zypitamag) Pravastati...
A small study of atorvastatin, which has a long half-life, found no significant differences whether it was administered in the morning or the evening [19]. Alternative Dosing Regimens Although statin Effect on LDL Cholesterol The statins are currently the most powerful approved drugs for lowering ...
Whereas one retrospective study indicated that all statins are associated with ocular side effects, atorvastatin showed higher incidences of muscle and liver problems (Mizranita and Pratisto, 2015). Age-related cataracts have occurred more frequently in patients receiving statin therapy (Machan et al....
Effects of simvastatin administration on rodents with lipopolysaccharide-induced liver microvascular dysfunction. Hepatology. 2013;57:1172–81. Google Scholar Wagner AH, Schwabe O, Hecker M. Atorvastatin inhibition of cytokine inducible nitric oxide synthase expression in native endothelial cells in situ....
lower in the atorvastatin group than in the MCAO group, suggesting a decrease in microglia with a proinflammatory phenotype (Zhang et al.2021). In vivo and in vitro studies have also shown that simvastatin can promote anti-inflammatory effects in microglia by stimulating the expression of PPARγ...
Potent inhibitors of cytochrome P450 (CYP) 3A4 significantly increase plasma concentrations of the active forms of simvastatin, lovastatin, and atorvastatin. Fluvastatin is metabolized by CYP2C9, whereas pravastatin, rosuvastatin, and pitavastatin are unaffected by inhibition by either CYP. Statins also...
We noted that the pattern of side-effects associated with statins resembles the pathology of selenium deficiency, and postulated that the mechanism lay in a well established, but often overlooked, biochemical pathway—the isopentenylation of selenocysteine-tRNA[Ser]Sec. A negative effect of statins ...