Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of premature death and disability; statin medications can reduce this risk and prevent heart disease. How Do Statins Work? Statin medications are a class of lipid-lowering medications that inhibit a step used by the liver to ...
Statin medications, a cornerstone of ASCVD prevention and treatment strategies, have been demonstrated to cause hyperglycemia and new onset diabetes mellitus (NODM). The purpose of this review is to summarize existing and emerging knowledge around the intersection of statins and these two important ...
“The main difference between the two analyses is that loss-of-function mutations are really more detrimental than common variants, meaning they mimic change that is often induced by medications,” he said. “We believe that the true effect lies closer to the loss-of-function mutation ...
In patients not achieving adequate lipid control on a maximally tolerated statin, nonstatin medications, including ezetimibe and proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors, provide enhanced low-density lipoprotein cholesterol reduction and cardiovascular benefits, especially in high-risk...
Clinical Outcomes and Adherence to Medications Measured by Claims Data in Patients With Diabetes OBJECTIVE—Although poor medication adherence may contribute to inadequate diabetes control, ways to feasibly measure adherence in routine clinical practic... M Pladevall,LK Williams,LA Potts,... - 《Diabe...
Beyond lowering cholesterol, statin medications have been found to have numerous other health benefits, including lowering a healthy man's risk of developing advanced prostate cancer, as well as lowering his prostate-specific antigen (PSA) levels.
“While statins and anti-hypertensives are incredibly cheap, they could be free,” she said. “We as a society could suggest that these medications – because of their outsized benefit for prevention, and because [cardiovascular disease] is the leading cause of death in this country – should...
(71.7%) referred to risk compensation behaviors in which patients engage in behaviors such as poor diet and physical inactivity while perceiving themselves to be protected or at lower risk by virtue of taking preventative medications.38Most tweets (666 of 1097 [60.7%]) did so without clarity of...
Statins are the most common medications prescribed for treatment of lipid disorders to reduce cardiovascular risk. In this chapter, the types and classes of statins are presented. The major statin trials conducted over the last 30 years are then summarized, with an emphasis on the relation of sta...
Men using cholesterol-lowering statin medications have been found to have lower risks of both advanced and fatal prostate cancer in multiple registry-based studies and prospective cohort studies. Statin use has also been associated with longer survival among men already diagnosed with prostate cancer. ...