Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of premature death and disability; statin medications can reduce this risk and prevent heart disease. How Do Statins Work? Statin medications are a class of lipid-lowering medications that inhibit a step used by the liver to ...
Statin medications, a cornerstone of ASCVD prevention and treatment strategies, have been demonstrated to cause hyperglycemia and new onset diabetes mellitus (NODM). The purpose of this review is to summarize existing and emerging knowledge around the intersection of statins and these two important ...
“The main difference between the two analyses is that loss-of-function mutations are really more detrimental than common variants, meaning they mimic change that is often induced by medications,” he said. “We believe that the true effect lies closer to the loss-of-function mutation ...
Beyond lowering cholesterol, statin medications have been found to have numerous other health benefits, including lowering a healthy man's risk of developing advanced prostate cancer, as well as lowering his prostate-specific antigen (PSA) levels. But a new study by researchers at Henry Ford Hospit...
“While statins and anti-hypertensives are incredibly cheap, they could be free,” she said. “We as a society could suggest that these medications – because of their outsized benefit for prevention, and because [cardiovascular disease] is the leading cause of death in this country – should...
In patients not achieving adequate lipid control on a maximally tolerated statin, nonstatin medications, including ezetimibe and proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors, provide enhanced low-density lipoprotein cholesterol reduction and cardiovascular benefits, especially in high-risk...
(71.7%) referred to risk compensation behaviors in which patients engage in behaviors such as poor diet and physical inactivity while perceiving themselves to be protected or at lower risk by virtue of taking preventative medications.38Most tweets (666 of 1097 [60.7%]) did so without clarity of...
Define Statins. Statins synonyms, Statins pronunciation, Statins translation, English dictionary definition of Statins. n. Any of a class of lipid-lowering drugs that reduce serum cholesterol levels by inhibiting a key enzyme involved in the biosynthesis
Statins are the most common medications prescribed for treatment of lipid disorders to reduce cardiovascular risk. In this chapter, the types and classes of statins are presented. The major statin trials conducted over the last 30 years are then summarized, with an emphasis on the relation of sta...
(PCSK9) inhibitors, etc.] should increase the pharmacological effectiveness of this approach and improve long-term outcomes in patients with CVD. In our opinion, the addition of statin drugs to an already existing regimen of anti-atherosclerotic medications should pose no problems with current ...