A meta-analysis of older patients included in randomised trials found good evidence that statins reduce vascular events and mortality in people with existing coronary heart disease. In older adults, exposure to higher doses of statins or higher potency statins does not increase their effectiveness, ...
In addition, few trials have specifically analyzed the efficacy of statins in older patients. This review summarizes the data relevant to the use of statins for the primary and secondary prevention of cardiovascular disease in older adults as well as some of the controversies regarding possible ...
Statins appear to reduce the risk of cancer, particularly lung and colorectal disease, in older adults 来自 Ingenta 喜欢 0 阅读量: 4 年份: 2008 收藏 引用 批量引用 报错 分享 全部来源 求助全文 Ingenta 相似文献Statins and cancer prevention....
"More research is needed, butstatinscould be a therapeutic option in the future to help reduce the effects of parkinsonism in the general population of older adults, not just people with high cholesterol or who are at risk for stroke," Oveisgharan said. "At a minimum, our study suggests b...
More information:Statins for primary prevention of cardiovascular events and mortality in old and very old adults: retrospective cohort study,www.bmj.com/content/362/bmj.k3359 Editorial: Primary prevention with statins for older adults,
These aids would be more useful if quality-of-life data were collected in statin trials and could be added to decision-making tools. In addition, consideration should be given to deprescribing statins for adults 76 years or older, other older individuals unlikely to derive benefit from statins ...
Lemaitre RN, Psaty BM, Heckbert SR, Kronmal RA, Newman AB, Burke GL: Therapy with hydroxymethylglutaryl coenzyme a reductase inhibitors (statins) and associated risk of incident cardiovascular events in older adults: evidence from the Cardiovascular Health Study. Arch Intern Med. 2002, 162: 1395...
Recommendations to treat older adults with hydroxymethylglutaryl coenzyme A reductase inhibitors (statins) for the primary prevention of coronary heart dis... RN Lemaitre - 《Archives of Internal Medicine》 被引量: 278发表: 2002年 Impact of systemic hypertension on the cardiovascular benefits of statin...
To help clinicians individualize statin therapy for primary prevention in older adults, we conducted a survival meta-analysis of the major randomized clinical trials to determine the TTB for statins, which we defined as the time from statin initiation to the prevention of a first MACE. We focused...
Awaiting the verdict: Statins and the road ahead for primary prevention in older adults 来自 EBSCO 喜欢 0 阅读量: 6 作者:MJR Aliberti,CAM Tavares,NM Pajewski 摘要: This editorial comments on the article by Orkaby et al. in this issue....