Statin drugs list Statin medications that are approved for use in the U.S. include: Altocor Crestor Lescol Lipitor Livalo Mevacor Pravachol Zocor Since their arrival on the market, statins have been among the most prescribed drugs in the U.S., with up to 92 million users. ...
Using the two drugs in combination usually results in the same side effects as those caused by statins alone – primarily muscle pain and stomach problems. Talk to your doctor if you'd like to try this. List of statins There are many different types of statins. The five types available ...
In 1929, Schoenheimer reported that mammals not only synthesize cholesterol de novo but also absorb dietary cholesterol from the intestine while excluding dietary plant sterols [1]. Both dietary cholesterol consumption and intestinal cholesterol absorption contribute to plasma cholesterol concentrations. Ezeti...
American Journal of Cardiovascular Drugs 9 , 103-107 /Friend AS, Kamalesh M, Schellhase E, Eckert GJ, Evans TS. Effect of time to titration to maximum dose of statins on cardiovascular outcomes: a retrospective analysis in high-risk patients. Am J Cardiovasc Drugs. 2009;9(2):103-7....
A Systematic Review of Cost-Effectiveness of Non-Statin Lipid-Lowering Drugs for Primary and Secondary Prevention of Cardiovascular Disease in Patients with Type 2 Diabetes Mellitus 2023, Current Problems in Cardiology Citation Excerpt : We also noted that in a study by Marquina et al. which exclud...
Investigational LDL Cholesterol–Lowering Drugs Currently in Cardiovascular Outcome Trials Bempedoic acid Bempedoic acid is a prodrug, converted in the liver to its coenzyme A conjugate, an inhibitor of adenosine triphosphate–citrate lyase. This enzyme acts at an earlier step than 3-hydroxy 3-methylglu...
In analysis of the 2-year statin-users cohort, we excluded individuals who used drugs from this class for less than 2 years and determined the adjusted risk of outcomes between statin users and nonusers. Statistical Analysis Baseline characteristics of the groups were compared using χ2 analysis...
Analysis of large genomic datasets can provide an alternative approach to investigating the mechanisms of action and repurposing potential of drugs. Genome-wide association studies (GWAS) have guided drug repurposing strategies for several diseases, with a notable example being the repurposing of a psori...
It reports the growth of sales performance of these cholesterol-lowering statin drugs. It reveals that the said drugs were recognized as a medical breakthrough for cardiovascular disease (CVD). It offers information about the need to know to make an informed decision in reducing or even eliminate...
The inability of nilotinib to inhibit mitochondria function might be due to the lack of specificity of ABL ATP-competitive inhibitors, as these drugs inhibit multiple enzymes other than ABL in solid tumors, and/or the inability of nilotinib to disrupt interactions with specific ABL downstream ...