Statin drugs list Statin medications that are approved for use in the U.S. include: Altocor Crestor Lescol Lipitor Livalo Mevacor Pravachol Zocor Since their arrival on the market, statins have been among the most prescribed drugs in the U.S., with up to 92 million users. ...
Using the two drugs in combination usually results in the same side effects as those caused by statins alone – primarily muscle pain and stomach problems. Talk to your doctor if you'd like to try this. List of statins There are many different types of statins. The five types available ...
Lipid-lowering agents also known ascholesterol-lowering, hypolipidemic, or antihyperlipidemic agents are a group of drugs used to reduce high levels oflipids(fats) and lipoproteins (fats with protein) in the blood. These drugs are used to treatcardiovascularabnormalities such asatherosclerosis(build-up...
In analysis of the 2-year statin-users cohort, we excluded individuals who used drugs from this class for less than 2 years and determined the adjusted risk of outcomes between statin users and nonusers. Statistical Analysis Baseline characteristics of the groups were compared using χ2 analysis...
In 1929, Schoenheimer reported that mammals not only synthesize cholesterol de novo but also absorb dietary cholesterol from the intestine while excluding dietary plant sterols [1]. Both dietary cholesterol consumption and intestinal cholesterol absorpti
American Journal of Cardiovascular Drugs 9 , 103-107 /Friend AS, Kamalesh M, Schellhase E, Eckert GJ, Evans TS. Effect of time to titration to maximum dose of statins on cardiovascular outcomes: a retrospective analysis in high-risk patients. Am J Cardiovasc Drugs. 2009;9(2):103-7....
Statins were also proclaimed as wonder drugs, influencing a wide range of physiological, biochemical and biological functions. The list appears to be long ... C Chiang,D Pella,RB Singh - 《Journal of Nutritional & Environmental Medicine》 被引量: 15发表: 2004年 Are statins really wonder drugs...
Investigational LDL Cholesterol–Lowering Drugs Currently in Cardiovascular Outcome Trials Bempedoic acid Bempedoic acid is a prodrug, converted in the liver to its coenzyme A conjugate, an inhibitor of adenosine triphosphate–citrate lyase. This enzyme acts at an earlier step than 3-hydroxy 3-methylglu...
Analysis of large genomic datasets can provide an alternative approach to investigating the mechanisms of action and repurposing potential of drugs. Genome-wide association studies (GWAS) have guided drug repurposing strategies for several diseases, with a notable example being the repurposing of a psori...
The inability of nilotinib to inhibit mitochondria function might be due to the lack of specificity of ABL ATP-competitive inhibitors, as these drugs inhibit multiple enzymes other than ABL in solid tumors, and/or the inability of nilotinib to disrupt interactions with specific ABL downstream ...