Out of all the statins, atorvastatin (Lipitor), simvastatin (Zocor), and lovastatin (Altoprev) have the strongest interaction with grapefruit, and this is likely to be true for other citrus. Grapefruit juice and any grapefruit products should be avoided, as should large quantities of limes or...
However, both 20a and 20b were about 20-fold less potent than mevastatin (IC50=0.03 μM) after hydrolysis of the lactone to the corresponding hydroxy-acids. Sign in to download full-size image Figure 9. Structures of key compounds and structure–activity relationships leading to the discovery ...
Cholesterol may be ingested in animal products, but less than twenty percent of your body's cholesterol needs will be supplied in this way. Your body then makes up the difference. If you eat less cholesterol, your body merely compensates by making more. Although the media and food companies ...
The truth is that NO woman should ever be given Lipitor or any other statin drug for elevated cholesterol. Dr. Rose says, “There are no statin trials with even the slightest hint of a mortality benefit in women and women should be told so”. (5). In other words,statin drugs don’t ...
self-reported atorvastatin use, the agreement with detection was 90.2%. However, when no statin use was reported, 42.4% of the samples had detectable levels of statins, with a similar range of concentrations as the samples from the self-reported statin users. The method is highly applicable in...